Add to ORKGAbstract Cyclic AMP powerfully inhibits the fMet-Leu-Phe-dependent respiratory burst and exocytosis of azurophilic and specific granules without affecting Ca2+ release from intracellular stores. The elevation of [Ca2+]i induced by fMet-Leu-Phe is short-lived in cyclic AMP-treated cells and similar to that of untreated cells stimulated in the absence of external Ca2+. Nevertheless, in these latter cells fMet-Leu-Phe induces metabolic activation. We therefore suggest that the inhibitory action of cyclic AMP on neutrophil responses is not due to its effects on [Ca2+]i homoeostasis
Human neutrophilic polymorphonuclear leukocytes (neutrophils) are terminally differentiated cells th...
Low concentrations of phorbol 12-myristate 13-acetate (PMA) elicit a specific response in human neut...
It has long been assumed that a rise in cytosolic free Ca2+, [Ca2+]i, is a necessary and sufficient ...
Cyclic AMP powerfully inhibits the fMet-Leu-Phe-dependent respiratory burst and exocytosis of azurop...
It has long been known that intracellular cAMP inhibits and cGMP enhances intact neutrophil function...
Abstract The effect of increased intracellular levels of cyclic AMP on phosphoinositide metabolism ...
It has long been known that Intracellular cAMP inhibits and cGMP enhances intact neutrophil function...
The effect of increased intracellular levels of cyclic AMP on phosphoinositide metabolism was studie...
We have studied how cytosolic free Ca2 " ([Ca2+Ii) changes and phorbol myristate acetate (PMA) ...
Item does not contain fulltextThe immature megakaryoblastic cell line MEG-01 responds to iloprost wi...
The relationship between fMet-Leu-Phe-induced changes in the cytosolic free Ca2+ concentration [( Ca...
AbstractThe role of extracellular calcium in the activation of respiratory burst in human neutrophil...
The concentration of cytosolic ionized calcium, [Ca2+]i, was measured in intact neutrophils by use o...
Verapamil inhibits in human neutrophils the respiratory burst, the secretion and the change of trans...
AbstractHuman neutrophils underwent spontaneous apoptosis, which was accompanied by degradation of M...
Human neutrophilic polymorphonuclear leukocytes (neutrophils) are terminally differentiated cells th...
Low concentrations of phorbol 12-myristate 13-acetate (PMA) elicit a specific response in human neut...
It has long been assumed that a rise in cytosolic free Ca2+, [Ca2+]i, is a necessary and sufficient ...
Cyclic AMP powerfully inhibits the fMet-Leu-Phe-dependent respiratory burst and exocytosis of azurop...
It has long been known that intracellular cAMP inhibits and cGMP enhances intact neutrophil function...
Abstract The effect of increased intracellular levels of cyclic AMP on phosphoinositide metabolism ...
It has long been known that Intracellular cAMP inhibits and cGMP enhances intact neutrophil function...
The effect of increased intracellular levels of cyclic AMP on phosphoinositide metabolism was studie...
We have studied how cytosolic free Ca2 " ([Ca2+Ii) changes and phorbol myristate acetate (PMA) ...
Item does not contain fulltextThe immature megakaryoblastic cell line MEG-01 responds to iloprost wi...
The relationship between fMet-Leu-Phe-induced changes in the cytosolic free Ca2+ concentration [( Ca...
AbstractThe role of extracellular calcium in the activation of respiratory burst in human neutrophil...
The concentration of cytosolic ionized calcium, [Ca2+]i, was measured in intact neutrophils by use o...
Verapamil inhibits in human neutrophils the respiratory burst, the secretion and the change of trans...
AbstractHuman neutrophils underwent spontaneous apoptosis, which was accompanied by degradation of M...
Human neutrophilic polymorphonuclear leukocytes (neutrophils) are terminally differentiated cells th...
Low concentrations of phorbol 12-myristate 13-acetate (PMA) elicit a specific response in human neut...
It has long been assumed that a rise in cytosolic free Ca2+, [Ca2+]i, is a necessary and sufficient ...