Abstract The intracellularly trappable fluorescent Ca2+ indicator quin-2 was used to measure free cytosolic Ca2+, [Ca2+]i, in the two highly dedifferentiated tumor cell lines, Ehrlich and Yoshida ascites carcinomas. It was found that these carcinoma cells can trap quin-2 similarly to normal cells, but [Ca2+]i was apparently significantly lower than in any normal cell tested previously with this method. By using a new lipid-soluble heavy metal chelator TPEN (N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine), which crosses artificial and natural membranes, it was found that endogenous heavy metals are responsible for partially quenching quin-2 fluorescence trapped inside the cells. Although the quenching of intracellular quin-2 fluorescenc...
The ability of cadmium to disrupt calcium homeostasis has been known since a long time, but the prec...
WOS: 000351020100005PubMed ID: 25535724Introduction: The measurement of intracellular Ca2+, cytosoli...
Human lung adenocarcinoma A549 cells sensitive and A549yDDP cells resistant to Cis-dichlorodiammine ...
A new, fluorescent, highly selective Ca2+ indicator , "quin2", has been trapped inside intact mouse ...
Using the membrane-permeant chelator of heavy metal ions, N,N,N',N'-tetrakis(2-pyridylmethyl)ethylen...
Using the membrane-permeant chelator of heavy metal ions, N,N,N\u27,N\u27- tetrakis(2-pyridylmethyl)...
In studies about the effects of heavy metals on intracellular Ca2+, the use of fluorescent probes is...
Drug resistance is a fundamental problem in cancer chemotherapy. Intracellular calcium concentration...
Exposure of cultured Chinese hamster ovary (CHO) cells to hydrogen peroxide results in the productio...
Intracellular calcium concentration ([Ca2+](i)) may have an important role in the development of che...
<p>To examine the [Ca<sup>2+</sup>]<sub>cyt</sub>, the fluorescent dye Fluo-3AM was incubated with (...
Intracellular Ca(2+) signaling is involved in a series of physiological and pathological processes. ...
Background: Knowledge of differences in the cellular physiology of malignant and non-malignant cells...
The determination of the cytotoxic potential of new and so far unknown compounds as well as their me...
To investigate the presence and the size of different non-mitochondrial Ca2+ pools of Ehrlich ascite...
The ability of cadmium to disrupt calcium homeostasis has been known since a long time, but the prec...
WOS: 000351020100005PubMed ID: 25535724Introduction: The measurement of intracellular Ca2+, cytosoli...
Human lung adenocarcinoma A549 cells sensitive and A549yDDP cells resistant to Cis-dichlorodiammine ...
A new, fluorescent, highly selective Ca2+ indicator , "quin2", has been trapped inside intact mouse ...
Using the membrane-permeant chelator of heavy metal ions, N,N,N',N'-tetrakis(2-pyridylmethyl)ethylen...
Using the membrane-permeant chelator of heavy metal ions, N,N,N\u27,N\u27- tetrakis(2-pyridylmethyl)...
In studies about the effects of heavy metals on intracellular Ca2+, the use of fluorescent probes is...
Drug resistance is a fundamental problem in cancer chemotherapy. Intracellular calcium concentration...
Exposure of cultured Chinese hamster ovary (CHO) cells to hydrogen peroxide results in the productio...
Intracellular calcium concentration ([Ca2+](i)) may have an important role in the development of che...
<p>To examine the [Ca<sup>2+</sup>]<sub>cyt</sub>, the fluorescent dye Fluo-3AM was incubated with (...
Intracellular Ca(2+) signaling is involved in a series of physiological and pathological processes. ...
Background: Knowledge of differences in the cellular physiology of malignant and non-malignant cells...
The determination of the cytotoxic potential of new and so far unknown compounds as well as their me...
To investigate the presence and the size of different non-mitochondrial Ca2+ pools of Ehrlich ascite...
The ability of cadmium to disrupt calcium homeostasis has been known since a long time, but the prec...
WOS: 000351020100005PubMed ID: 25535724Introduction: The measurement of intracellular Ca2+, cytosoli...
Human lung adenocarcinoma A549 cells sensitive and A549yDDP cells resistant to Cis-dichlorodiammine ...