Multifocal adenomatous oncocytic hyperplasia of the parotid gland: case report

Oncocytes appear as the principal component in some pathological con- ditions of the salivary glands including diffuse oncocytosis, oncocytic metaplasia, oncocytoma, oncocytic carcinoma, and multifocal adenomatous oncocytic hyper- plasia. Oncocytic tumors rarely affect the major salivary glands, accounting less than 1% of all salivary gland tumours. Multifocal adenomatous oncocytic hyperplasia in the salivary glands is an extremely rare condition. The differential diagnosis of the clear cell variant includes many malignant salivary gland tumors. We report a new case of multifocal adenomatous oncocytic hyperplasia of the parotid gland in a 64-year-old man. The differential histopathogenesis, diagnosis, and treatment of this rare entity are discussed. c 2005 Elsevier Ltd. All rights reserved