An innovative earthquake resistant steel frame with reinforced concrete infill walls system is presented. The system is conceived to ensure the formation of diagonal struts in the infill walls by eliminating the connectors with the lateral columns and by suitably placing stiffeners and bearing plates in the beam-to-column joints. Energy dissipation should take place mainly in the vertical steel elements without involving the reinforcements of the infill walls. Specific rules for capacity design are presented and the results of nonlinear numerical simulations to assess the behaviour of the system are briefly discussed