Reaction of ortho-azidohetaren carbaldehydes with bis(trimethylsilyl)sulfide: a novel route to fused isothiazoles

  • DEGL'INNOCENTI, Alessandro
  • FUNICELLO, Maria
  • SCAFATO, Patrizia
  • SPAGNOLO, Piero
Publication date
January 1994
Publisher
The Chemical Society of Japan

Abstract

o-Azidohetarenecarbaldehydes react with bis(trimethylsiyl) sulfide and hydrochloric acid to give fused isothiazoles in yields strongly dependent upon the nature of the heteroaromatic ring through intramolecular cyclization reaction of presumable intermediate o-azidocarbothialdehydes

Extracted data

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