Bipolar disorder (BD) has been suggested to be associated with accelerated aging and premature cell senescence. While findings on shorter telomeres in BD are controversial, a recent study showed that long-term lithium treatment correlates with longer telomeres in BD. In our study, we sought to investigate the correlation between leukocyte telomere length (LTL) and long-term lithium treatment in a sample of 200 BD patients characterized for lithium response. We also compared data from two different methods commonly used to measure telomere length, quantitative PCR (qPCR) and quantitative fluorescence in situ hybridization (Q-FISH). We also measured, for the first time, the effect of lithium in vitro on the expression of the telomerase gene i...
Bipolar Disorder (BD) has recently been related to a process of accelerated aging, with shortened le...
Telomere length is a promising biomarker for age-related disease and a potential anti-ageing drug ta...
Background: Telomeres are protective DNA-protein complexes at the ends of each chromosome, maintaine...
Bipolar disorder (BD) has been suggested to be associated with accelerated aging and premature cell ...
Aim: To assess the role of lithium treatment in the relationship between bipolar disorder (BD) and l...
Telomeres consist of exanucleotide tandem repeats and proteins complexes at the end of chromosome en...
Background It has been suggested that bipolar disorder (BD) is associated with clinical and biologic...
Bipolar disorder (BD) is a severe psychiatric illness affecting approximately 1%-2% of individuals w...
Background: Bipolar disorder is a common, chronic and severe mental illness, causing suffering and ...
Psychiatric disorders seem to be characterized by premature cell senescence. However, controversial ...
Variation in telomere length is heritable and is currently considered a promising biomarker of susce...
Objective: Bipolar disorder (BD) has been associated with increased rates of age-related diseases, s...
Psychiatric disorders seem to be characterized by premature cell senescence. However, controversial ...
Objective: Bipolar disorder (BD) has been associated with increased rates of age-related diseases, s...
Objective: The findings of telomere length (TL) studies in bipolar disorder (BD) are controversial. ...
Bipolar Disorder (BD) has recently been related to a process of accelerated aging, with shortened le...
Telomere length is a promising biomarker for age-related disease and a potential anti-ageing drug ta...
Background: Telomeres are protective DNA-protein complexes at the ends of each chromosome, maintaine...
Bipolar disorder (BD) has been suggested to be associated with accelerated aging and premature cell ...
Aim: To assess the role of lithium treatment in the relationship between bipolar disorder (BD) and l...
Telomeres consist of exanucleotide tandem repeats and proteins complexes at the end of chromosome en...
Background It has been suggested that bipolar disorder (BD) is associated with clinical and biologic...
Bipolar disorder (BD) is a severe psychiatric illness affecting approximately 1%-2% of individuals w...
Background: Bipolar disorder is a common, chronic and severe mental illness, causing suffering and ...
Psychiatric disorders seem to be characterized by premature cell senescence. However, controversial ...
Variation in telomere length is heritable and is currently considered a promising biomarker of susce...
Objective: Bipolar disorder (BD) has been associated with increased rates of age-related diseases, s...
Psychiatric disorders seem to be characterized by premature cell senescence. However, controversial ...
Objective: Bipolar disorder (BD) has been associated with increased rates of age-related diseases, s...
Objective: The findings of telomere length (TL) studies in bipolar disorder (BD) are controversial. ...
Bipolar Disorder (BD) has recently been related to a process of accelerated aging, with shortened le...
Telomere length is a promising biomarker for age-related disease and a potential anti-ageing drug ta...
Background: Telomeres are protective DNA-protein complexes at the ends of each chromosome, maintaine...