Isonicotinoylhydrazothiazoles and isonicotinoyl-N-4-substituted thiosemicarbazides: Synthesis, characterization, and anti-mycobacterial activity

CARDIA, MARIA CRISTINA
DISTINTO, SIMONA
MACCIONI, ELIAS
PLUMITALLO, ANTONIO
SANNA, MARIA LUISA
DE LOGU, ALESSANDRO
Saddi M

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Publication date

January 2006

DOI

10.1002/jhet.5570430529

ISSN

0022-152X

Abstract

Differently substituted isonicotinoylhydrazothiazoles and isonicotinoyl-N4-substituted thiosemicarbazides have been prepared and characterized by means of elemental analysis, 1H-NMR, 13C-NMR, and Mass spectrometry. All the synthesised compounds have been screened in order to evaluate their antimycobacterial activity in vitro. Some of the new compounds showed activity towards M. tuberculosis H37R and M. Marinum in the millimolar range

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Isonicotinoylhydrazothiazoles and isonicotinoyl-N-4-substituted thiosemicarbazides: Synthesis, characterization, and anti-mycobacterial activity

Abstract

Extracted data

Isonicotinoylhydrazothiazoles and isonicotinoyl-N-4-substituted thiosemicarbazides: Synthesis, characterization, and anti-mycobacterial activity

Abstract

Extracted data

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