Addiction as a psychiatric disorder involves interaction of inherited predispositions and environmental factors. Similarly to humans, laboratory animals self-administer addictive drugs, whose appetitive properties result from activation and suppression of brain reward and aversive pathways, respectively. The ventral tegmental area (VTA) where dopamine (DA) cells are located is a key component of brain reward circuitry, whereas the rostromedial tegmental nucleus (RMTg) critically regulates aversive behaviors. Reduced responses to either aversive intrinsic components of addictive drugs or to negative consequences of compulsive drug taking might contribute to vulnerability to addiction. In this regard, female Lister Hooded (LH) rats are more v...
<p>Dopamine regulates movement, cognition and the rewarding effects of addictive drugs. Sex differen...
Many studies have provided evidence for important sex-dependent differences in the origins, outcomes...
Abstract Background Glutamate signaling within the nucleus accumbens underlies motivated behavior an...
Addiction as a psychiatric disorder involves interaction of inherited predispositions and environmen...
Sex-dependent differences have been consistently described in cannabinoid addiction research. In par...
Sex-dependent differences are frequently observed in the biological and behavioural effects of subst...
The present study examined differences in operant responses in adult male and female rats during dis...
Animal and human studies have shown that sex and hormones are key factors in modulating addiction. P...
The present study examined differences in operant responses in adult male and female rats during dis...
Addiction is a psychiatric disorder, whose aetiology involves interaction of inherited predispositio...
Abstract Background Several chronic pain disorders, such as migraine and fibromyalgia, have an incre...
An increasing body of evidence shows significant sex differences in the mammalian brain in multiple ...
IntroductionClinically relevant sex differences have been noted in a number of affective, behavioral...
Women are at greater risk for cocaine addiction than are men, and female rats similarly show a great...
Sex differences in behavioural patterns of drug abuse and dependence have been hypothesized to be a ...
<p>Dopamine regulates movement, cognition and the rewarding effects of addictive drugs. Sex differen...
Many studies have provided evidence for important sex-dependent differences in the origins, outcomes...
Abstract Background Glutamate signaling within the nucleus accumbens underlies motivated behavior an...
Addiction as a psychiatric disorder involves interaction of inherited predispositions and environmen...
Sex-dependent differences have been consistently described in cannabinoid addiction research. In par...
Sex-dependent differences are frequently observed in the biological and behavioural effects of subst...
The present study examined differences in operant responses in adult male and female rats during dis...
Animal and human studies have shown that sex and hormones are key factors in modulating addiction. P...
The present study examined differences in operant responses in adult male and female rats during dis...
Addiction is a psychiatric disorder, whose aetiology involves interaction of inherited predispositio...
Abstract Background Several chronic pain disorders, such as migraine and fibromyalgia, have an incre...
An increasing body of evidence shows significant sex differences in the mammalian brain in multiple ...
IntroductionClinically relevant sex differences have been noted in a number of affective, behavioral...
Women are at greater risk for cocaine addiction than are men, and female rats similarly show a great...
Sex differences in behavioural patterns of drug abuse and dependence have been hypothesized to be a ...
<p>Dopamine regulates movement, cognition and the rewarding effects of addictive drugs. Sex differen...
Many studies have provided evidence for important sex-dependent differences in the origins, outcomes...
Abstract Background Glutamate signaling within the nucleus accumbens underlies motivated behavior an...