Menopause and quality of life: Effects of tibolone (Article) [Menopausa e qualità della vita: Effetti del tibolone]

Menopause is associated with symptoms caused by estrogen deficiency. These symptoms may have a negative impact on overall quality of life of a menopausal woman. Hot flashes, sweating, sleep disturbances and vaginal dryness are common symptoms. Decreased sexual desire is related to both estrogen and androgen deficiency. Climacteric syndrome includes also mood disturbances. Hormonal Replacement Therapy (HRT) improves many of these symptoms. Tibolone, through its estrogenic and androgenic activities, is able to improve significantly these problems, including decreased libido, obtaining a positive effect on overall quality of life in menopause