New Treatment Schemes for Yaws: The Path Toward Eradication
- MITJÀ O
- HAYS R
- MCDERMOT R
- BASSAT Q.
- RINALDI, ANDREA
DOIAbstract
Yaws—an infectious disease caused by Treponema pallidum subsp. pertenue—is a paradigmatic example of the neglected tropical disease and is reemerging as a public health concern in many countries, causing suffering particularly in children aged <15 years of age in poor rural communities. However, its global eradication, a goal since 1950, may now be closer than ever as a result of the recent expansion and simplification of treatment options to include oral azithromycin. Indeed, the results of a trial published last January [1] allow certain optimism about the treatment and eradication of this ancient disease because a simple single-dose oral treatment targeting whole populations could be sufficient to adequately cure the infection in its ear...
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