The nucleus accumbens has been subdivided into a shell and a core compartment on the basis of histochemical and connectional differences. Recently, we reported that behavioral sensitization to morphine is associated with an increased dopamine transmission in the caudate-putamen and in the nucleus accumbens core as well as a decreased response in the nucleus accumbens shell following acute morphine challenge. We have now performed a similar study in rats sensitized to amphetamine and to cocaine. Behavioral sensitization was induced by daily administration of a single dose of 1 mg/kg s.c. of amphetamine for 10 days or of 10 mg/kg i.p. of cocaine twice a day for 14 days. Microdialysis was performed 10-14 days after the last injection of amphet...
Addictive Substances like morphine and psychostimulants induce a preferential increase in dopamine (...
Repeated exposure to drugs of abuse causes persistent behavioural sensitization and associated adapt...
The use of inbred rat strains provides a tool to investigate the role of genetic factors in drug abu...
In this study, we describe a model of opiate sensitization characterized by a brief schedule of trea...
In this study, we describe a model of opiate sensitization characterized by a brief schedule of trea...
We have recently reported that behavioural sensitization to morphine, amphetamine, cocaine and nicot...
We have recently reported that behavioural sensitization to morphine, amphetamine, cocaine and nicot...
Alterations in dopamine transmission in the nucleus accum-bens, which is composed of two anatomicall...
Stimuli conditioned (CS’s) by pavlovian association with drugs of abuse are thought to play an impor...
Stimuli conditioned (CS’s) by pavlovian association with drugs of abuse are thought to play an impor...
The selectively bred Roman high- and low-avoidance rats differ in emotionality and responsiveness to...
The selectively bred Roman high- and low-avoidance rats differ in emotionality and responsiveness to...
The nucleus accumbens is considered a critical target of the action of drugs of abuse. In this nucle...
The nucleus accumbens is considered a critical target of the action of drugs of abuse. In this nucle...
Addictive Substances like morphine and psychostimulants induce a preferential increase in dopamine (...
Addictive Substances like morphine and psychostimulants induce a preferential increase in dopamine (...
Repeated exposure to drugs of abuse causes persistent behavioural sensitization and associated adapt...
The use of inbred rat strains provides a tool to investigate the role of genetic factors in drug abu...
In this study, we describe a model of opiate sensitization characterized by a brief schedule of trea...
In this study, we describe a model of opiate sensitization characterized by a brief schedule of trea...
We have recently reported that behavioural sensitization to morphine, amphetamine, cocaine and nicot...
We have recently reported that behavioural sensitization to morphine, amphetamine, cocaine and nicot...
Alterations in dopamine transmission in the nucleus accum-bens, which is composed of two anatomicall...
Stimuli conditioned (CS’s) by pavlovian association with drugs of abuse are thought to play an impor...
Stimuli conditioned (CS’s) by pavlovian association with drugs of abuse are thought to play an impor...
The selectively bred Roman high- and low-avoidance rats differ in emotionality and responsiveness to...
The selectively bred Roman high- and low-avoidance rats differ in emotionality and responsiveness to...
The nucleus accumbens is considered a critical target of the action of drugs of abuse. In this nucle...
The nucleus accumbens is considered a critical target of the action of drugs of abuse. In this nucle...
Addictive Substances like morphine and psychostimulants induce a preferential increase in dopamine (...
Addictive Substances like morphine and psychostimulants induce a preferential increase in dopamine (...
Repeated exposure to drugs of abuse causes persistent behavioural sensitization and associated adapt...
The use of inbred rat strains provides a tool to investigate the role of genetic factors in drug abu...