By using a novel and versatile capillary microfluidic flow-focusing device we fabricated monodisperse drug-loaded nanoparticles from biodegradable polymers. A model amphiphilic drug (dexamethasone) was incorporated within the biodegradable matrix of the particles. The effects of flow rate ratio, polymer concentration and microreactor focusing channel dimensions on nanoparticles size and drug loading have been investigated. The presented data demonstrate that the microfluidic approach resulted in the production of colloidal nanoparticles with a narrow size distribution and useful morphological characteristics.This approach allows the rapid, easy, low cost and automated synthesis of polymeric nanoparticles, thus it may become a useful approac...
Biodegradable poly(DL-lactic acid) (PLA) and poly(lactic-co-glycolic acid) (PLGA) microparticles wit...
The rise of polypharmacy and knowledge of pharmacogenetics has the potential to revolutionise dosing...
The aim of this study was to develop a new microfluidic approach for the preparation of nanoparticle...
Microreactors have been shown to be a powerful tool for the production of nanoparticles (NPs); howev...
Microfluidic synthesis of nanoparticles (NPs) can enhance the controllability and reproducibility in...
Biodegradable poly(DL-lactic acid) (PLA) and poly(lactic-co-glycolic acid) (PLGA) microparticles wit...
The development of a microfluidic-based process is presented for the production ofnanomaterials in c...
Synthetic polymeric biodegradable nanoparticles were produced by micromixing combined with nanopreci...
Polymeric micro- and nanoparticles have attracted a wide attention of researchers in various areas s...
Microfluidic-assisted particle fabrication provides a route to circumvent the disadvantages associat...
Capillary-based flow-focusing and co-flow microsystems were developed to produce sphere-like polymer...
Biodegradable poly(dl-lactic acid) (PLA) and poly(lactic-<i>co</i>-glycolic acid) (PLGA) micropart...
The goal of this research is to implement and optimize the operating conditions of a microfluidic mi...
In this study, a microfluidic device was employed to produce polymeric nanoparticles (NPs) with well...
This paper reviews the latest developments in microfluidic devices for synthesizing nanoparticles an...
Biodegradable poly(DL-lactic acid) (PLA) and poly(lactic-co-glycolic acid) (PLGA) microparticles wit...
The rise of polypharmacy and knowledge of pharmacogenetics has the potential to revolutionise dosing...
The aim of this study was to develop a new microfluidic approach for the preparation of nanoparticle...
Microreactors have been shown to be a powerful tool for the production of nanoparticles (NPs); howev...
Microfluidic synthesis of nanoparticles (NPs) can enhance the controllability and reproducibility in...
Biodegradable poly(DL-lactic acid) (PLA) and poly(lactic-co-glycolic acid) (PLGA) microparticles wit...
The development of a microfluidic-based process is presented for the production ofnanomaterials in c...
Synthetic polymeric biodegradable nanoparticles were produced by micromixing combined with nanopreci...
Polymeric micro- and nanoparticles have attracted a wide attention of researchers in various areas s...
Microfluidic-assisted particle fabrication provides a route to circumvent the disadvantages associat...
Capillary-based flow-focusing and co-flow microsystems were developed to produce sphere-like polymer...
Biodegradable poly(dl-lactic acid) (PLA) and poly(lactic-<i>co</i>-glycolic acid) (PLGA) micropart...
The goal of this research is to implement and optimize the operating conditions of a microfluidic mi...
In this study, a microfluidic device was employed to produce polymeric nanoparticles (NPs) with well...
This paper reviews the latest developments in microfluidic devices for synthesizing nanoparticles an...
Biodegradable poly(DL-lactic acid) (PLA) and poly(lactic-co-glycolic acid) (PLGA) microparticles wit...
The rise of polypharmacy and knowledge of pharmacogenetics has the potential to revolutionise dosing...
The aim of this study was to develop a new microfluidic approach for the preparation of nanoparticle...