Introduction. The use of psychoactive substances is one of the leading factors in the deterioration of the mental health of the population. The dynamics of addictive morbidity in recent years is closely correlated with each other, as well as with other manifestations of social problems: the general mortality of the population; the number of suicides; the number of crimes committed, which in general affects the development of the country. Materials and methods. The material of the study was statistical data, scientific literature, regulatory documents, and Internet sources. In studying of the problem, used retrospective, documentary, normative and legal, forensic and pharmaceutical methods of analysis. Results and discussion. The article p...