Add to ORKGPotential theranostic agents based on metal organic frame works (MOFs) are currently used for the targeted drug delivery at specific disease sites. Their microporous structure, chemical functionality and thermal stability make them an exceptional candidate in the biomedical field. Zeolitic imidazolate framework-8 (ZIF-8) is a prominent bio compatible MOF. The present work reports the in-situ incorporation of novel anti-cancer drug, doxorubicin (Dox) in the ZIF-8 structure using a simple solvothermal route. The nanoparticle size was found to be around 100-150 nm as confirmed by XRD and SEM. The inherent red luminescence of Doxorubicin helps in probing the nanoparticles. The amount of Dox in ZIF 8 frame is quantified from the fluorescence int...
The zeolitic imidazolate framework (ZIF-8), composed of zinc ion and dimethylimidazole, is widely us...
The drug resistance of bacteria is a significant threat to human civilization while the action of an...
Multiple drug resistance is a persistent obstacle for efficient chemotherapy of cancer. Herein, we r...
Combination therapy has been regarded as a promising strategy for cancer treatment due to the enhanc...
A multifunctional diagnosis and treatment integration platform is crucial in cancer treatments. Here...
Zeolitic imidazolate framework (ZIF-8) has been synthesized at room temperature in aqueous medium. T...
We have developed a general synthetic route to encapsulate small molecules in monodisperse zeolitic ...
Nanoscale size controllable and surface modifiable zeolitic imidazolate framework-8–poly(acrylic ac...
Abstract Chemo-photothermal therapy based on nanoparticles has emerged as a promising strategy for c...
Conventional organic and inorganic drug nanocarriers suffer from serious drawbacks such as low drug-...
Many medical and chemical applications require target molecules to be delivered in a controlled mann...
In the last decade, nanosized metal organic frameworks (NMOFs) have gained an increasing applicabili...
The effective chemotherapy treatment for liver cancer patients remains an urgent issue due to the di...
High porosities, large surface areas, and tunable functionalities made metal–organic frameworks (MOF...
The zeolitic imidazolate framework-8 (ZIF-8) is a specifically promising drug carrier due to its exc...
The zeolitic imidazolate framework (ZIF-8), composed of zinc ion and dimethylimidazole, is widely us...
The drug resistance of bacteria is a significant threat to human civilization while the action of an...
Multiple drug resistance is a persistent obstacle for efficient chemotherapy of cancer. Herein, we r...
Combination therapy has been regarded as a promising strategy for cancer treatment due to the enhanc...
A multifunctional diagnosis and treatment integration platform is crucial in cancer treatments. Here...
Zeolitic imidazolate framework (ZIF-8) has been synthesized at room temperature in aqueous medium. T...
We have developed a general synthetic route to encapsulate small molecules in monodisperse zeolitic ...
Nanoscale size controllable and surface modifiable zeolitic imidazolate framework-8–poly(acrylic ac...
Abstract Chemo-photothermal therapy based on nanoparticles has emerged as a promising strategy for c...
Conventional organic and inorganic drug nanocarriers suffer from serious drawbacks such as low drug-...
Many medical and chemical applications require target molecules to be delivered in a controlled mann...
In the last decade, nanosized metal organic frameworks (NMOFs) have gained an increasing applicabili...
The effective chemotherapy treatment for liver cancer patients remains an urgent issue due to the di...
High porosities, large surface areas, and tunable functionalities made metal–organic frameworks (MOF...
The zeolitic imidazolate framework-8 (ZIF-8) is a specifically promising drug carrier due to its exc...
The zeolitic imidazolate framework (ZIF-8), composed of zinc ion and dimethylimidazole, is widely us...
The drug resistance of bacteria is a significant threat to human civilization while the action of an...
Multiple drug resistance is a persistent obstacle for efficient chemotherapy of cancer. Herein, we r...