Attenuation of IL-1β-induced MMP-3 mRNA expression in other sets of melanoma cells transfected with p65/RelA siRNA, but not with p105 siRNA.
- Junichi Nunomura (11648959)
- Rei Nakano (820735)
- Atsuto Naruke (11648956)
- Yoko Suwabe (9468965)
- Masumi Nakano (11648962)
- Naoya Yachiku (10098508)
- Manami Kuji (10098511)
- Mana Sugimura (10098514)
- Shinichi Namba (3350288)
- Taku Kitanaka (3350276)
- Nanako Kitanaka (3350285)
- Hiroshi Sugiya (412101)
- Tomohiro Nakayama (30894)
Publication date
November 2022
DOI Publisher
Public Library of Science (PLoS)Abstract
Melanoma cells (a, CMe1; b, eCMMe2; c, LMe) transfected with p65/RelA, p105, or scrambled siRNAs following the stimulation of IL-1β (100 pM) for 24 h. Relative expression of MMP-3 mRNA was evaluated. TBP was used as a reference. The attenuation of MMP-3 expression was observed in p65/RelA-depleted cells but not in the cells transfected with p105 siRNA or scrambled siRNA. The results are represented as mean ± standard error (SE) of biological triplicates. *P<0.05.</p
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