Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In addition, it is one of the pathways by which doxorubicin, one of the anticancer drugs commonly used, negatively impacts the cardiac muscle, leading to cardiac function impairment. This side effect limits the use of doxorubicin. Iron chelators play an important role in hindering ferritinophagy. Antioxidants can also impact ferritinophagy by improving oxidative stress. In this study, it was assumed that the antioxidant function of melatonin could promote the action of deferoxamine, an iron chelator, at the level of ferritinophagy. A total of 42 male Wistar rats (150–200 g) were divided into seven groups (n = 6) which consisted of group I: control norm...
Adriamycin is a first line cancer treatment drug for breast cancer and many soft tissue carcinomas. ...
Heart failure (HF) is a highly complex disorder and a major end-point of cardiovascular diseases (CV...
Iron chelators are used to treat iron overload cardiomyopathy patients. However, a direct comparison...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Doxorubicin (DOX) is commonly used for the treatment of hematological and solid tumors. However, the...
Copyright © 2012 Othman A. Al-Shabanah et al. This is an open access article distributed under the C...
The present study was designed to explore the protective effects of melatonin and its analogs, 6-hyd...
Purpose: Doxorubicin, as an effective chemotherapeutic drug, is commonly used for combating various ...
Due to the cardiotoxicity of doxorubicin (DOX), its clinical application is limited. Lipid peroxidat...
Adriamycin is a first line cancer treatment drug for breast cancer and many soft tissue carcinomas. ...
Heart failure (HF) is a highly complex disorder and a major end-point of cardiovascular diseases (CV...
Iron chelators are used to treat iron overload cardiomyopathy patients. However, a direct comparison...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In additio...
Doxorubicin (DOX) is commonly used for the treatment of hematological and solid tumors. However, the...
Copyright © 2012 Othman A. Al-Shabanah et al. This is an open access article distributed under the C...
The present study was designed to explore the protective effects of melatonin and its analogs, 6-hyd...
Purpose: Doxorubicin, as an effective chemotherapeutic drug, is commonly used for combating various ...
Due to the cardiotoxicity of doxorubicin (DOX), its clinical application is limited. Lipid peroxidat...
Adriamycin is a first line cancer treatment drug for breast cancer and many soft tissue carcinomas. ...
Heart failure (HF) is a highly complex disorder and a major end-point of cardiovascular diseases (CV...
Iron chelators are used to treat iron overload cardiomyopathy patients. However, a direct comparison...