Enrichment of differentially expressed genes amongst differentially methylated foetal genes in cell subpopulations following MIA at different gestational timepoints.

(A) Enrichment of upregulated genes among differentially methylated foetal genes following MIA at GD9. Size of the circles represents the number of overlapping genes. The dashed line is set at FDR = 0.05. (B) Enrichment of upregulated genes among differentially methylated foetal genes following MIA at GD17. Size of the circles represents the number of overlapping genes. The dashed line is set at FDR = 0.05. (C) Enrichment of downregulated genes among differentially methylated foetal genes following MIA at GD17. Sizes of the circles represents the number of overlapping genes. The dashed line is set at FDR = 0.05. (D) The intersect of enriched genes differentially methylated following MIA at both GD9 and GD17.