(A) C vs HR mice with and without wheel access. (B) Normal vs mini-muscle individuals with or without wheel access. Values are 1 + log10 transformed LS means ± standard errors from SAS Procedure Mixed ANCOVA. DG = deep gastrocnemius, SG = superficial gastrocnemius, PL = plantaris, SL = soleus.</p
(A) ATPase staining of gastrocnemius muscle. Black areas, type I fibers. White areas, type IIa fiber...
<p>A) Electron micrographs of gastrocnemius muscle. Left (a,c,e,g), ×5,200; right (b,d,f,h), a highe...
Genotypes of the recorded animals are given in the table. Values show mean ± standard error of the m...
<p>Quantification based on images obtained using the modified Gomori trichrome stain on transverse s...
<p>Bar histograms quantifying the diameters of fast muscle fibers in the peroneus (Pero), lateral ga...
<p><b>(A-D)</b> Sirius red staining of gastrocnemius muscle from wild-type (120 days old) and sympto...
<p>Representative images of transverse sections of triceps (A) or quadriceps (B) muscles from 12-wee...
<p>Fiber number is calculated by dividing muscle CSA by the average fiber cross-sectional area.</p
<p>(A) Wet weights of gastrocnemius muscles from 4 week-old <i>Hgs</i><sup><i>+/+</i></sup> and <i>H...
<p>There are no error bars on some of the graphs (D,F) as the myofibre types were present in less th...
<p>Mean ± SEM. *, †, and §: p<0.05 vs. control muscle, type P fibers, and ∼40% central-nucleated fib...
<p>Serial sections from the soleus (A, B and E, F) and gastronemius (C, D and G, H) muscles stained ...
<p><b>(a)</b> Representative pictures of laminin-stained gastrocnemius and triceps from 34 weeks old...
<p>Values are expressed as mean±SD or median (25th percentile, 75th percentile). Abbreviations: CSA,...
<p>(<b>A</b>) Morphometric analysis of muscle fibre cross-sectional area in the soleus and quadricep...
(A) ATPase staining of gastrocnemius muscle. Black areas, type I fibers. White areas, type IIa fiber...
<p>A) Electron micrographs of gastrocnemius muscle. Left (a,c,e,g), ×5,200; right (b,d,f,h), a highe...
Genotypes of the recorded animals are given in the table. Values show mean ± standard error of the m...
<p>Quantification based on images obtained using the modified Gomori trichrome stain on transverse s...
<p>Bar histograms quantifying the diameters of fast muscle fibers in the peroneus (Pero), lateral ga...
<p><b>(A-D)</b> Sirius red staining of gastrocnemius muscle from wild-type (120 days old) and sympto...
<p>Representative images of transverse sections of triceps (A) or quadriceps (B) muscles from 12-wee...
<p>Fiber number is calculated by dividing muscle CSA by the average fiber cross-sectional area.</p
<p>(A) Wet weights of gastrocnemius muscles from 4 week-old <i>Hgs</i><sup><i>+/+</i></sup> and <i>H...
<p>There are no error bars on some of the graphs (D,F) as the myofibre types were present in less th...
<p>Mean ± SEM. *, †, and §: p<0.05 vs. control muscle, type P fibers, and ∼40% central-nucleated fib...
<p>Serial sections from the soleus (A, B and E, F) and gastronemius (C, D and G, H) muscles stained ...
<p><b>(a)</b> Representative pictures of laminin-stained gastrocnemius and triceps from 34 weeks old...
<p>Values are expressed as mean±SD or median (25th percentile, 75th percentile). Abbreviations: CSA,...
<p>(<b>A</b>) Morphometric analysis of muscle fibre cross-sectional area in the soleus and quadricep...
(A) ATPase staining of gastrocnemius muscle. Black areas, type I fibers. White areas, type IIa fiber...
<p>A) Electron micrographs of gastrocnemius muscle. Left (a,c,e,g), ×5,200; right (b,d,f,h), a highe...
Genotypes of the recorded animals are given in the table. Values show mean ± standard error of the m...