Effects of age on the urinary excretion of total and non-dialyzable hydroxyproline
- Minisola, Salvatore
- R., Antonelli
- A., Scarpiello
- C., Medori
- C., Valtorta
- G., Mazzuoli
DOIAbstract
This study was carried out in order to investigate the effects of age on the urinary excretion of total and non-dialyzable hydroxyproline (OHPr) in normal subjects. We found that total urinary OHPr was negatively correlated with age but, by means of partial regression analysis, no correlation was found after correction for changes in creatinine clearance; on the contrary, non-dialyzable OHPr showed a statistically significant negative correlation with age (r=-0.56) even when creatinine clearance was held constant (p<0.05). A highly significant direct correlation was found between total and non-dialyzable OHPr in the whole group (r=0.54) and when only premenopausal women and men under 60 years of age were considered (r=0.51). No correlation ...
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