Female ‘hysteria’ has presented a fascinating medical mystery since its early and Ancient origins. It was first thought to be caused by the uterus moving around the body, but the aetiology of this disease has been ever shifting, and was interpreted in many different ways by many different people. This thesis examines hysteria from 1603 to 1682, from Edward Jorden to Thomas Sydenham, and the ways in which the social, political, and medical contexts of the time shaped understandings of the disease. It begins with Edward Jorden and his use of hysteria as a defence for witchcraft in the case of Elizabeth Jackson. It then proceeds to examine the lives and work of three scholars who interacted with Oxford University—William Harvey, Nathaniel High...