Effectiveness of Pipelle as Endometrial Sampling Procedure in Comparison with Dilatation and Curettage

Background: To determine safety and effectiveness ofpipelle for taking endometrial biopsy as out patientprocedure in comparison with dilatation and curettage(D&C).Methods: In this comparative study, detailed clinicalevaluation of 80 patients was done to establish indicationfor endometrial sampling. Subjects were divided into 2groups.In 1st group pipelle (n=40)procedure wasperformed as outpatient procedure without analgesiaunder aseptic conditions.Biopsies were taken and sent forhistopathology and for acid fast bacilli in cases ofinfertility .Subjects were retained for 30 min to observe forany complication. In 2nd group (n=40) patients wereadmitted from out patient department and D&C done onvery next day in operation theatre as formal procedureunder anaesthesia .Patients were retained in ward afterprocedure to observe any post operative complications forone day. Samples were sent for histopathology . ChiSquare test was used for statistical analysis.Results: There was no case of perforation in bothgroups.In first group of Pipelle 36 cases had nopain.When compared to second group statisticalsignificance was .000. Mild bleeding was observed in 2cases of pipelle as compared to 4 cases of 2nd group.Sample was adequate in 37 cases of pipelle while in 39cases of D&C .Histopathology report when compared in 2groups showed statistical significant difference was 0. 05.Conclusion: Endometrial Biopsy with Pipelle is safe,efficient and cost effective means of evaluating uterineendometrium It is associated with minimal discomfort,adequate sampling without need of anaesthesia