Add to ORKG2-cephem allylic bromides are important, versatile intermediates for the derivatization of C-3’ position in cephalosporines. We showed that they can react smoothly with phenols, yielding the C-3’ cephem derivatives by C-alkylation of phenols
Reaction of a 2β-bromomethyl penam with triphenyltin hydride gave, via ring expansion of the derived...
text(-) Codeine, (-) morphine, and their semi-synthetic derivatives play an integral role in medicin...
Incubation of penicillin N (3a) with partially purified deacetoxy/deacetylcephalosporin C synthase (...
3-Bromomethyl-3 cephems are solvolysed by alcohols, similarly to the Δ2 isomers. The yields are fai...
Bromination of cepham I with 2,6-lutidine Br complex gave II (R = Br), which was treated with DMF/H2...
Synthetic studies towards the total synthesis of ($-$)-Cephalotaxine are described. The key chemical...
Cephalosporolide B (Ces-B) was efficiently synthesized and exploited for the first time as a versati...
Cephalotaxiane and a variety of (alpha)-hydroxysuccinate esters of cephalotaxine known as the harrin...
In efforts to synthesize haloperidol analogues with improved properties as HIV protease inhibitors, ...
Two practical routes to (6S,7S)-cephalosporins from 6-aminopenicillanic acid (6-APA) are described. ...
A mild and operationally simple method for the chemoselective esterification of phenolic alcohols is...
The first example of the synthesis of <i>m</i>-alkylphenols via a ruthenium-catalyzed C<sub>Ar</sub>...
Enzymatic synthesis of cephalosporins is hampered by secondary hydrolysis and by complicated down-st...
This thesis is concerned with studies on the enzyme carbamoyl transferase (CT) of the C cephalospori...
The synthesis of a putative intramolecular Diels-Alder reaction substrate, an intermediate in a synt...
Reaction of a 2β-bromomethyl penam with triphenyltin hydride gave, via ring expansion of the derived...
text(-) Codeine, (-) morphine, and their semi-synthetic derivatives play an integral role in medicin...
Incubation of penicillin N (3a) with partially purified deacetoxy/deacetylcephalosporin C synthase (...
3-Bromomethyl-3 cephems are solvolysed by alcohols, similarly to the Δ2 isomers. The yields are fai...
Bromination of cepham I with 2,6-lutidine Br complex gave II (R = Br), which was treated with DMF/H2...
Synthetic studies towards the total synthesis of ($-$)-Cephalotaxine are described. The key chemical...
Cephalosporolide B (Ces-B) was efficiently synthesized and exploited for the first time as a versati...
Cephalotaxiane and a variety of (alpha)-hydroxysuccinate esters of cephalotaxine known as the harrin...
In efforts to synthesize haloperidol analogues with improved properties as HIV protease inhibitors, ...
Two practical routes to (6S,7S)-cephalosporins from 6-aminopenicillanic acid (6-APA) are described. ...
A mild and operationally simple method for the chemoselective esterification of phenolic alcohols is...
The first example of the synthesis of <i>m</i>-alkylphenols via a ruthenium-catalyzed C<sub>Ar</sub>...
Enzymatic synthesis of cephalosporins is hampered by secondary hydrolysis and by complicated down-st...
This thesis is concerned with studies on the enzyme carbamoyl transferase (CT) of the C cephalospori...
The synthesis of a putative intramolecular Diels-Alder reaction substrate, an intermediate in a synt...
Reaction of a 2β-bromomethyl penam with triphenyltin hydride gave, via ring expansion of the derived...
text(-) Codeine, (-) morphine, and their semi-synthetic derivatives play an integral role in medicin...
Incubation of penicillin N (3a) with partially purified deacetoxy/deacetylcephalosporin C synthase (...