Pathophysiological changes in ionic currents lead to a pattern of tissue automaticity dependent on the degree of intercellular coupling.
- Chiara Campana (14149829)
- Eugenio Ricci (14149832)
- Chiara Bartolucci (8710578)
- Stefano Severi (544174)
- Eric A. Sobie (242595)
Publication date
November 2022
DOI Publisher
Public Library of Science (PLoS)Abstract
(A) Effect of L-type Ca2+ current (ICaL) perturbation in the Fabbri tissue model (σ equal to 0.1). (B) Effect of perturbation in ICaL and Na+/K+ pump (INaK) in the Maltsev-Lakatta tissue model (σ equal to 0.4). (C) Effect of combined ICaL, rapid delayed rectifier K+ current (IKr), and INaK perturbation in the Severi tissue model (σ equal to 0.2).</p
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