Cadmium Intake, Dietary Patterns and Hyperuricemia Among Adults in China

Blood and urine cadmium levels have been found to be positively associated with hyperuricemia (HU) in some studies. Few studies have examined the association between dietary cadmium intake, dietary patterns and HU in the Chinese population. The study analysed data from 8429 adults who participated in the China Health and Nutrition Survey (CHNS). Dietary intake was assessed by 3-day 24 h food record in seven waves of survey (1991, 1993, 1997, 2000, 2004, 2006 and 2009). Serum uric acid was measured in 2009. Dietary pattern was identified using factor analysis. The association between cumulative dietary cadmium intake, dietary patterns and HU was assessed using logistic regression. In total, 1737 (16.3%) participants had HU in the study sample. After adjusting for demographic, lifestyle factors (i.e. smoking, alcohol drinking, physical activity) and chronic conditions, the OR for HU was 2.25 (95%CI 1.84–2.77, p for trend Other Information Published in: Exposure and Health License: https://creativecommons.org/licenses/by/4.0See article on publisher's website: http://dx.doi.org/10.1007/s12403-020-00375-4