We introduce a novel compartmental model accounting for the effects of vaccine efficacy, deployment rates and timing of initiation of deployment. We simulate different scenarios and initial conditions, and we find that higher abundancy and rate of deployment of low efficacy vaccines lowers the cumulative number of deaths in comparison to slower deployment of high efficacy vaccines. We also forecast that, at the same daily deployment rate, the earlier introduction of vaccination schemes with lower efficacy would also lower the number of deaths with respect to a delayed introduction of high efficacy vaccines, which can however, still achieve lower numbers of infections and better herd immunity
The administration of vaccines against the coronavirus disease 2019 (COVID-19) started in early Dece...
Whether the protection afforded by a vaccine wanes over time and if so, by how much, are important p...
, and have been calibrated for such settings. Their applicability to low transmission settings is un...
<div><p>(A) The morbidity-based strategy is more effective than the mortality-based strategy when <i...
Vaccine effect, as measured in clinical trials, may not accurately reflect population-level impact. ...
During pandemic influenza, several factors could significantly impact the outcome of vaccination cam...
Abstract. During pandemic influenza, several factors could significantly im-pact the outcome of vacc...
Abstract Background There is great interest in the use of reduced dosing schedules for pneumococcal ...
Developing accurate and reliable methods to estimate vaccine protection is a key goal in immunology ...
Several factors have played a strong role in influencing the dynamics of COVID-19 in the U.S. One be...
Limited production capacity and delays inherent in vaccine development are major hurdles to the wide...
<p>Colors in each panel represent the cumulative incidence ratio, comparing cumulative incidence amo...
© 2018 Elsevier Ltd Background: Motivated by the unexplained variation in the performance of some va...
Different strategies have been used to maximise the effect of COVID-19 vaccination campaigns in Euro...
The authors consider estimability and interpretation of vaccine efficacy based on time to event data...
The administration of vaccines against the coronavirus disease 2019 (COVID-19) started in early Dece...
Whether the protection afforded by a vaccine wanes over time and if so, by how much, are important p...
, and have been calibrated for such settings. Their applicability to low transmission settings is un...
<div><p>(A) The morbidity-based strategy is more effective than the mortality-based strategy when <i...
Vaccine effect, as measured in clinical trials, may not accurately reflect population-level impact. ...
During pandemic influenza, several factors could significantly impact the outcome of vaccination cam...
Abstract. During pandemic influenza, several factors could significantly im-pact the outcome of vacc...
Abstract Background There is great interest in the use of reduced dosing schedules for pneumococcal ...
Developing accurate and reliable methods to estimate vaccine protection is a key goal in immunology ...
Several factors have played a strong role in influencing the dynamics of COVID-19 in the U.S. One be...
Limited production capacity and delays inherent in vaccine development are major hurdles to the wide...
<p>Colors in each panel represent the cumulative incidence ratio, comparing cumulative incidence amo...
© 2018 Elsevier Ltd Background: Motivated by the unexplained variation in the performance of some va...
Different strategies have been used to maximise the effect of COVID-19 vaccination campaigns in Euro...
The authors consider estimability and interpretation of vaccine efficacy based on time to event data...
The administration of vaccines against the coronavirus disease 2019 (COVID-19) started in early Dece...
Whether the protection afforded by a vaccine wanes over time and if so, by how much, are important p...
, and have been calibrated for such settings. Their applicability to low transmission settings is un...