Earthworm coelomocytes - characteristics, function and application in research

Gujavice su mali, detritovorni beskralježnjaci koji pripadaju koljenu kolutićavaca (Annelida). Celomociti čine imunološke stanice gujavica. One su mezenhimskog podrijetla i sastavni su dio celomske tekućine. Zbog manjka usuglašenosti, postoje više različitih načina na koje se celomociti mogu podijeliti. Unatoč manjku ujednačene podjele, celomociti pokazuju karakteristike kao što su proliferacija, termoadaptabilnost, regeneracija, fluorescencija, preživljavanje u uvjetima mikrogravitacije i slične. Celomociti su za gujavice važne jer sudjeluju u izbjegavanju osmotskog stresa, antifugalnom djelovanju, te se ističu svojom aktivnošću u imunitetu gujavica. Gujavice posjeduju stanični imunitet u kojem celomociti obnašaju funkciju fagocitoze, stvaranja smeđih tijela, odbacivanja stranog tkiva i druge, dok humoralni imunitet obuhvaća stvaranje različitih vrsta humoralnih faktora. Iako se za celomocite već odavno zna, u novije vrijeme otkrilo se nekoliko spoznaja kako ove stanice mogu biti primjenjene i u raznim istarživanjima.Earthworms are small, detrital invertebrates that are categorized as Annelids. Coelomocytes are earthworm immune cells. They are of mesenchymal origin, form coelomic fluid, and are located in the coelom. Due to the lack of consistency, there are several different ways in which they can be divided. Despite the lack of uniform division, whole cells show characteristics such as proliferation, thermoadaptability, regeneration, fluorescence, survival under microgravity conditions, and other. Cellocytes are important for earthworms because they participate in the avoidance of osmotic stress, antifungal action, and are distinguished by their activity in the immunity of earthworms. Earthworms possess cellular immunity in which coelomocytes play a role in phagocytosis, creation of brown bodies, rejection of foreign tissue, and similar, while humoral immunity encompasses creating various kinds of humoral factors. Although earthworm coelomocytes are not a novelty, recently there have been several novel dicoveries for their application in research