The effectiveness of hyaluronic acid for knee osteoarthritis therapy

CILJ ISTRAŽIVANJA: ispitati učinkovitost hijaluronata u smanjenju bolova kod pacijenata s osteoartrozom koljenog zgloba tako što će se uspoređivati razina bola prije te nakon aplikacije hijaluronata intraartikularno. NACRT STUDIJE: Istraživanje je provedeno kao presječna studija na 33 osobe u dobi između 26 i 73 godine. ISPITANICI I METODE: Istraživanjem su obuhvaćeni pacijenti s osteoartritisom koljenog zgloba koji su liječeni ambulantno aplikacijom hijaluronata (Suplasyn) u zglob preparatom od 2 ml u periodičnom razmaku od jednog tjedna u tri navrata u Zavodu za ortopediju i traumatologiju KBC-a Osijek unazad posljednja 3 mjeseca. Iz dostupne medicinske dokumentacije prikupljeni su opći podatci koji govore o spolu, dobi, lokalizaciji artroze, stupnju artroze te intenzitetu bola prije i poslije operacije po VAS skali te dužini trajanja ambulantne procedure. REZULTATI: Nakon aplikacije hijaluronske kiseline u koljeni zglob kod pacijenata mlađih od 66 godina sa stupnjem osteoartroze I i II po Kellgren-Lawrenceu dolazi do značajnog smanjenja osjeta bola definiranog VAS skalom od 1 do 10. ZAKLJUČAK: Liječenje osteoartroze koljena intraartikularnom aplikacijom hijaluronske kiseline uspješna je metoda jer dovodi značajnog smanjenja osjeta bola zahvaćenog zgloba.RESEARCH OBJECTIVES: To examine the effectiveness of hyalurons in reducing pain in patients with knee joint osteoarthrosis by comparing pain levels before and after application of hyaluronates intrarticularly. STUDY DESIGN: The study was conducted as a cross-section study on 33 patients between the ages of 26 and 73. PARTICIPANTS AND METHODS: The study included patients with knee joint osteoarthritis who were treated with an outpatient application of hyaluronates (Suplasyn) in the joint, a 2 ml preparation at a periodic interval of one week on three occasions at the Institute of Orthopaedics and Traumatology of the University hospital Osijek for the last 3 months. From the available medical documentation, general data that speak of gender, age, localization of arthrosis, degree of arthrosis, pain intensity before and after surgery on the VAS scale, and the duration of the outpatient procedure were collected. RESULTS: Following application of hyaluronic acid in the knee joint in patients under 66 years of age with osteoarthrosis grades I and II per Kellgren-Lawrence has a significant reduction in VAS - defined pain sensation from 1 to 10. CONCLUSION: Treatment of knee osteoarthrosis with intraarticular application of hyaluronic acid is a successful method as it leads to a significant reduction in the sensation of pain of the affected joint