The aim of this multicenter GIMEMA study was to correlate autoimmune complications (AIC) in B-cell chronic lymphocytic leukemia (B-CLL) with stage and therapy. Autoimmune hemolytic anemia (129/194 cases) and autoimmune thrombocytopenia (35/194 cases) were typically present in advanced and multi-treated disease. Age over the median, stage C and first and second line therapy were identified as independent risk factors by multivariate analysis. In contrast, non-hematologic AIC (30/194 cases) and the presence of serological markers of autoimmunity were mostly observed in early B-CLL, suggesting different pathogenic mechanisms underlying hematologic and non-hematologic autoimmune phenomena in B-CLL
Introduction: Chronic lymphocytic leukemia (CLL) is frequently complicated by cytopenias, either due...
Objective: To determine the frequency of presenting features and complication in chronic lymphocytic...
Anemia and thrombocytopenia at chronic lymphocytic leukemia (CLL) presentation have long been consid...
The aim of this multicenter GIMEMA study was to correlate autoimmune complications (AIC) in B-cell c...
The majority of disease-specific complications in chronic lymphocytic leukemia (CLL), notably infect...
Autoimmune complications are common in chronic lymphocytic leukemia (CLL), occurring in up to a quar...
Fifty-two cases of autoimmune hemolytic anemia (AHA) were observed within a series of 1203 patients ...
Fifty-two cases of autoimmune hemolytic anemia (AHA) were observed within a series of 1203 patients ...
Anemia, Hemolytic, Autoimmune; Databases, Factual; Humans; Immunoglobulin Heavy Chains; Immunoglobul...
CLL has been defined as presence of more than 5000 small mature appearing monoclonal B lymphocytes w...
Chronic lymphocytic leukemia (CLL) is frequently complicated by secondary autoimmune cytopenias (AIC...
BACKGROUND: Major infections (MIs), secondary cancers (SCs) and autoimmune diseases (ADs) are the mo...
The clinical course of chronic lymphocytic leukemia (CLL) may be complicated at any time by autoimmu...
The development of autoimmune hemolytic anemia (AIHA) in patients with chronic lymphocytic leukemia ...
The relationship of a number of subacute or chronic infectious diseases, connective tissue or autoim...
Introduction: Chronic lymphocytic leukemia (CLL) is frequently complicated by cytopenias, either due...
Objective: To determine the frequency of presenting features and complication in chronic lymphocytic...
Anemia and thrombocytopenia at chronic lymphocytic leukemia (CLL) presentation have long been consid...
The aim of this multicenter GIMEMA study was to correlate autoimmune complications (AIC) in B-cell c...
The majority of disease-specific complications in chronic lymphocytic leukemia (CLL), notably infect...
Autoimmune complications are common in chronic lymphocytic leukemia (CLL), occurring in up to a quar...
Fifty-two cases of autoimmune hemolytic anemia (AHA) were observed within a series of 1203 patients ...
Fifty-two cases of autoimmune hemolytic anemia (AHA) were observed within a series of 1203 patients ...
Anemia, Hemolytic, Autoimmune; Databases, Factual; Humans; Immunoglobulin Heavy Chains; Immunoglobul...
CLL has been defined as presence of more than 5000 small mature appearing monoclonal B lymphocytes w...
Chronic lymphocytic leukemia (CLL) is frequently complicated by secondary autoimmune cytopenias (AIC...
BACKGROUND: Major infections (MIs), secondary cancers (SCs) and autoimmune diseases (ADs) are the mo...
The clinical course of chronic lymphocytic leukemia (CLL) may be complicated at any time by autoimmu...
The development of autoimmune hemolytic anemia (AIHA) in patients with chronic lymphocytic leukemia ...
The relationship of a number of subacute or chronic infectious diseases, connective tissue or autoim...
Introduction: Chronic lymphocytic leukemia (CLL) is frequently complicated by cytopenias, either due...
Objective: To determine the frequency of presenting features and complication in chronic lymphocytic...
Anemia and thrombocytopenia at chronic lymphocytic leukemia (CLL) presentation have long been consid...