Increased expression of autophagic proteins in acute murine cholestasis.
- Colin T. Shearn (159797)
- Aimee L. Anderson (14124069)
- Michael W. Devereux (14124072)
- David J. Orlicky (7853594)
- Cole Michel (6383282)
- Dennis R. Petersen (159819)
- Colin G. Miller (14124075)
- Sanjiv Harpavat (3897)
- Edward E. Schmidt (11599441)
- Ronald J. Sokol (14124078)
Publication date
November 2022
DOI Publisher
Public Library of Science (PLoS)Abstract
A. qPCR analysis of mRNA for autophagic proteins in liver tissue isolated from 3-day sham and BDL adult mice (N = 5/group). Expression was normalized against HPRT. B. Western analysis of autophagic proteins in liver tissue isolated from BDL mice (N = 5/group). Blots were normalized to GAPDH expression. C. qPCR analysis of mRNA for autophagic proteins in liver tissue isolated from 10-week old Mdr2KO mice (N = 4/group). D. Western analysis of autophagic proteins in liver tissue isolated from 10 week on Mdr2KO mice (N = 6/group). Blots were normalized to GAPDH expression Data are presented as Mean ± STDEV and were statistically analyzed using a Student’s t-test, *p<0.05, **p<0.01, ***P<0.001, ****p<0.0001, N = 6/group.</p
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