Topical 5-fluorouracil for Basal Cell Carcinoma

Basal cell carcinoma is a malignant epithelial tumor arising only in skin, from the basal layer of the epidermis or of the pilosebaceous adnexa. Diagnosis often depends on skin examination, confirmed by tissue biopsy. Treatment is typically by surgical removal. This can be by simple excision if the cancer is small; otherwise Mohs surgery is generally recommended. Other options may include topical chemotherapy, laser therapy, or the use of imiquimod. In this study, we conclude topical 5-fluorouracil is a highly effective and well-tolerated treatment option for superficial basal cell carcinomas