Pulmonary arterial hypertension (PAH) is characterized by enhanced pulmonary vascular resistance, which causes right ventricular pressure overload and can lead to right-sided heart failure and death. A close link between PAH and cancer has been extensively suggested, with increasing evidence of a metabolic theory that underlies the pathogenesis of both diseases, mainly due to similarities in the processes responsible for triggering a hyperproliferative and apoptosis-resistant phenotype in both cardiopulmonary and malignant cells. Similar to cancer, abnormalities in mitochondrial biogenesis might lead to the following consequences: dysfunction of this organelle, which, in turn, causes the Warburg effect, a shift from mitochondrial respiratio...
A significant glycolytic shift in the cells of the pulmonary vasculature and right ventricle during ...
La survenue d’une défaillance ventriculaire droite est associée à une augmentation de mortalité dans...
Knowledge of the pathobiology of pulmonary hypertension (PH) continues to accelerate. However, funda...
Pulmonary arterial hypertension (PAH) is characterized by the increased pulmonary vascular resistanc...
In lung vascular cells, mitochondria serve a canonical metabolic role, governing energy homeostasis....
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated pulmonary a...
Background: The leading cause of mortality due to pulmonary arterial hypertension (PAH) is failure o...
Pulmonary arterial hypertension (PAH) is a vascular remodeling disease of the lungs resulting in hea...
Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy, characterized by exc...
Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy, characterized by exc...
Right ventricular dysfunction is the most frequent cause of death in patients with pulmonary arteria...
Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy, characterized by exc...
Calcium can be regulated by mitochondria and also plays a significant role in mitochondrial pathways...
Background: The leading cause of mortality due to pulmonary arterial hypertension (PAH) is failure o...
Pulmonary artery hypertension is characterized by proliferation in the resistance vessels. A recent ...
A significant glycolytic shift in the cells of the pulmonary vasculature and right ventricle during ...
La survenue d’une défaillance ventriculaire droite est associée à une augmentation de mortalité dans...
Knowledge of the pathobiology of pulmonary hypertension (PH) continues to accelerate. However, funda...
Pulmonary arterial hypertension (PAH) is characterized by the increased pulmonary vascular resistanc...
In lung vascular cells, mitochondria serve a canonical metabolic role, governing energy homeostasis....
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated pulmonary a...
Background: The leading cause of mortality due to pulmonary arterial hypertension (PAH) is failure o...
Pulmonary arterial hypertension (PAH) is a vascular remodeling disease of the lungs resulting in hea...
Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy, characterized by exc...
Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy, characterized by exc...
Right ventricular dysfunction is the most frequent cause of death in patients with pulmonary arteria...
Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy, characterized by exc...
Calcium can be regulated by mitochondria and also plays a significant role in mitochondrial pathways...
Background: The leading cause of mortality due to pulmonary arterial hypertension (PAH) is failure o...
Pulmonary artery hypertension is characterized by proliferation in the resistance vessels. A recent ...
A significant glycolytic shift in the cells of the pulmonary vasculature and right ventricle during ...
La survenue d’une défaillance ventriculaire droite est associée à une augmentation de mortalité dans...
Knowledge of the pathobiology of pulmonary hypertension (PH) continues to accelerate. However, funda...