The World Health Organization recommends pre-exposure prophylaxis (PrEP) for individuals at substantial risk of HIV infection. The aim of this analysis is to quantify the individual risk of HIV infection over time, using a large database of high-risk individuals (n = 5583). We used data from placebo recipients in five phase III PrEP trials: iPrEx, conducted in men who have sex with men and transgender women; VOICE, conducted in young women at high sexual risk; Partners PrEP, conducted in HIV serodiscordant heterosexual couples; TDF2, conducted in high-risk heterosexual men and women; and BTS, conducted in persons who inject drugs. The probability of HIV infection over time was estimated using NONMEM7.4. We identified predictors of HIV risk ...
Introduction: Despite a number of HIV prevention strategies, the number of new HIV infections remain...
Introduction. Guidelines for pre-exposure prophylaxis (PrEP) provide criteria to identify individual...
Risk compensation (RC) could reduce or offset the biological prevention benefits of HIV preexposure ...
The World Health Organization recommends pre-exposure prophylaxis (PrEP) for individuals at substant...
BackgroundFor maximum effect pre-exposure prophylaxis should be targeted to the subpopulations that ...
Prevention of type-1 human immunodeficiency virus (HIV) infections has primarily been through condom...
ObjectivesThe past decade has seen tremendous progress in the development of biomedical agents that ...
BackgroundThe effect of HIV pre-exposure prophylaxis (PrEP) depends on uptake, adherence, and sexual...
Randomized clinical trials of HIV prevention in high-risk populations of women often assume that all...
International audienceObjectives We aimed to assess among men who have sex with men (MSM) risk facto...
BACKGROUND: The potential for emergence and spread of HIV drug resistance from rollout of antiretrov...
Randomized clinical trials of HIV prevention in high-risk populations of women often assume that all...
Objectives: HIV pre-exposure prophylaxis (PrEP) may change serosorting patterns. We examined the inf...
<p>PrEP = pre-exposure prophylaxis; OR = odds ratio; CI = Confidence Interval; P = level of signific...
Introduction: Despite a number of HIV prevention strategies, the number of new HIV infections remain...
Introduction: Despite a number of HIV prevention strategies, the number of new HIV infections remain...
Introduction. Guidelines for pre-exposure prophylaxis (PrEP) provide criteria to identify individual...
Risk compensation (RC) could reduce or offset the biological prevention benefits of HIV preexposure ...
The World Health Organization recommends pre-exposure prophylaxis (PrEP) for individuals at substant...
BackgroundFor maximum effect pre-exposure prophylaxis should be targeted to the subpopulations that ...
Prevention of type-1 human immunodeficiency virus (HIV) infections has primarily been through condom...
ObjectivesThe past decade has seen tremendous progress in the development of biomedical agents that ...
BackgroundThe effect of HIV pre-exposure prophylaxis (PrEP) depends on uptake, adherence, and sexual...
Randomized clinical trials of HIV prevention in high-risk populations of women often assume that all...
International audienceObjectives We aimed to assess among men who have sex with men (MSM) risk facto...
BACKGROUND: The potential for emergence and spread of HIV drug resistance from rollout of antiretrov...
Randomized clinical trials of HIV prevention in high-risk populations of women often assume that all...
Objectives: HIV pre-exposure prophylaxis (PrEP) may change serosorting patterns. We examined the inf...
<p>PrEP = pre-exposure prophylaxis; OR = odds ratio; CI = Confidence Interval; P = level of signific...
Introduction: Despite a number of HIV prevention strategies, the number of new HIV infections remain...
Introduction: Despite a number of HIV prevention strategies, the number of new HIV infections remain...
Introduction. Guidelines for pre-exposure prophylaxis (PrEP) provide criteria to identify individual...
Risk compensation (RC) could reduce or offset the biological prevention benefits of HIV preexposure ...