The origins of SARS-CoV-2: a critical review
- Holmes, Edward C.
- Goldstein, Stephen A.
- Rasmussen, Angela L.
- Robertson, David L.
- Crits-Christoph, Alexander
- Wertheim, Joel O.
- Anthony, Simon J.
- Barclay, Wendy S.
- Boni, Maciej F.
- Doherty, Peter C.
- Farrar, Jeremy
- Geoghegan, Jemma L.
- Jiang, Xiaowei
- Leibowitz, Julian L.
- Neil, Stuart J.D.
- Skern, Tim
- Weiss, Susan R.
- Worobey, Michael
- Andersen, Kristian G.
- Garry, Robert F.
- Rambaut, Andrew
DOIAbstract
Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus in December 2019 in Wuhan, China, there has been intense interest in understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the human population. Recent debate has coalesced around two competing ideas: a “laboratory escape” scenario and zoonotic emergence. Here, we critically review the current scientific evidence that may help clarify the origin of SARS-CoV-2
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