Development and validation of models for optimisation and control of batch and continuous crystallisation processes

The work presented in this paper constitute the main results from the SINC-PRO project (IMS project focussing on crystalliser design and control) as regards off-line model use. A generic modelling framework applicable to a wide range of solution crystallisation processes is briefly presented. This framework enables the rapid development of consistent process models, which predict process behaviour and product performance (mainly in terms of CSD and purity) as a function of design and operational parameters