People that experience prenatal alcohol exposure (PAE) may have behavioral and metabolic impairments, and it is unclear whether these remain stable or change with age. We assessed behavioral and metabolic endpoints across the lifespan in a mouse model of fetal alcohol spectrum disorder (FASD). Pregnant C57BL/6J mice received alcohol (ALC; 3 g/kg) or maltose-dextrin (control, CON) daily from embryonic day 8.5 to 17.5. Offspring were tested on accelerating rotarod, Y-maze, novel object recognition, and fear conditioning at 6 weeks and 10 and 17 months; females were also tested at 24 months. Body composition, fasting glucose, and glucose clearance were assessed at 18 months. Female but not male ALC mice had greater adiposity than age-matched C...
Fetal Alcohol Spectrum Disorders (FASD) effect an estimated 2% of the population, causing a range of...
Maternal alcohol binge drinking during pregnancy can be deleterious for the developing foetus, leadi...
Fetal alcohol spectrum disorder (FASD) is a completely preventable disease, that has profound effect...
People that experience prenatal alcohol exposure (PAE) may have behavioral and metabolic impairments...
Although prenatal alcohol exposure (PAE) reduces offspring growth, it may increase obesity risk at a...
Background: Prenatal alcohol exposure (PAE) causes behavioral deficits and increases risk of metabol...
Prenatal exposure to ethanol can result in an abundance of psychological, physical and developmental...
Abstract The potential impact of prenatal alcohol exposure (PAE) varies considerably among exposed i...
Alcohol consumption during pregnancy can produce developmental abnormalities in offspring brain and ...
IntroductionPrenatal alcohol exposure (PAE) causes neuroinflammation that may contribute to the path...
IntroductionPrenatal alcohol exposure (PAE) causes neuroinflammation that may contribute to the path...
Prenatal and perinatal alcohol exposure caused by maternal alcohol intake during gestation and lacta...
Abstract Background The aim of this study was to investigate the effects of prenatal alcohol exposur...
Prenatal alcohol exposure (PAE) causes fetal growth restrictions. A major driver of fetal growth def...
Prenatal ethanol exposure (PrEE) is a leading cause of preventable birth defects and neurobehavioral...
Fetal Alcohol Spectrum Disorders (FASD) effect an estimated 2% of the population, causing a range of...
Maternal alcohol binge drinking during pregnancy can be deleterious for the developing foetus, leadi...
Fetal alcohol spectrum disorder (FASD) is a completely preventable disease, that has profound effect...
People that experience prenatal alcohol exposure (PAE) may have behavioral and metabolic impairments...
Although prenatal alcohol exposure (PAE) reduces offspring growth, it may increase obesity risk at a...
Background: Prenatal alcohol exposure (PAE) causes behavioral deficits and increases risk of metabol...
Prenatal exposure to ethanol can result in an abundance of psychological, physical and developmental...
Abstract The potential impact of prenatal alcohol exposure (PAE) varies considerably among exposed i...
Alcohol consumption during pregnancy can produce developmental abnormalities in offspring brain and ...
IntroductionPrenatal alcohol exposure (PAE) causes neuroinflammation that may contribute to the path...
IntroductionPrenatal alcohol exposure (PAE) causes neuroinflammation that may contribute to the path...
Prenatal and perinatal alcohol exposure caused by maternal alcohol intake during gestation and lacta...
Abstract Background The aim of this study was to investigate the effects of prenatal alcohol exposur...
Prenatal alcohol exposure (PAE) causes fetal growth restrictions. A major driver of fetal growth def...
Prenatal ethanol exposure (PrEE) is a leading cause of preventable birth defects and neurobehavioral...
Fetal Alcohol Spectrum Disorders (FASD) effect an estimated 2% of the population, causing a range of...
Maternal alcohol binge drinking during pregnancy can be deleterious for the developing foetus, leadi...
Fetal alcohol spectrum disorder (FASD) is a completely preventable disease, that has profound effect...