In this work, in two parts, we continue to develop the geometric theory of quantum PDE's, introduced by us starting from 1996. This theory has the purpose to build a rigorous mathematical theory of PDE's in the category $\mathfrak{D}_S$ of noncommutative manifolds ({\em quantum (super)manifolds}), necessary to encode physical phenomena at microscopic level (i.e., {\em quantum level}). Aim of the present paper is to report on some new issues in this direction, emphasizing an interplaying between surgery, integral bordism groups and conservations laws. In particular, a proof of the Poincar\'e conjecture, generalized to the category $\mathfrak{D}_S$, is given by using our geometric theory of PDE's just in such a category