Add to ORKGThiourea is a carbon, hydrogen, sulphur, and nitrogen-based organic molecule. The thiourea group has been improved by replacing various substituents for its hydrogen atoms at the nitrogen terminal, resulting in a wide range of biological activities, especially on anticancer properties. Despite the fact that thiourea derivatives have remarkable anticancer potential, finding a novel anticancer agent that is both safe and selective remains a challenge. This paper summarizes recent research on thiourea compounds that can be used to treat malignant cell lines. Several synthesis methods and the effects of substituents as well as their anticancer therapeutic potential in a variety of healthy and malignant cell lines are discussed. As a result, it ...
The specific objective of this research is to investigate the biological activity of thiourea deriva...
Two series of bis-substituted thiourea derivatives 40a-e and tri-substituted thiourea derivatives 42...
A series of 33 novel (thio)urea-containing compounds were initially designed and synthesized as pote...
Substituted thiourea derivatives possess confirmed cytotoxic activity towards cancer but also normal...
AbstractThioureas are important sulfur and nitrogen containing compounds and they are useful substan...
A novel series of sulfonamide derivatives (14 compounds) bearing thiourea moieties were efficiently ...
UnrestrictedCancer has emerged as one of the deadliest diseases in the recent past. According to the...
Urea and thiourea represent privileged structures in medicinal chemistry. Indeed, these moieties con...
Urea and thiourea represent privileged structures in medicinal chemistry. Indeed, these moieties con...
Introduction: Urea- and thiourea-based compound has shown a potency to be further developed as antic...
Abstract Background Various thiourea derivatives have been used as starting materials for compounds ...
Mutation of the proto-oncogene K-Ras is one of the most common molecular mechanisms in non-small cel...
A series of dehydroabietic acid (DHAA) acyl-thiourea derivatives were designed and synthesized as po...
Thiourea derivatives demonstrate potent cytotoxic activity against various leukemias and many tumor ...
Two series of bis-substituted thiourea derivatives 40a-e and tri-substituted thiourea derivatives 42...
The specific objective of this research is to investigate the biological activity of thiourea deriva...
Two series of bis-substituted thiourea derivatives 40a-e and tri-substituted thiourea derivatives 42...
A series of 33 novel (thio)urea-containing compounds were initially designed and synthesized as pote...
Substituted thiourea derivatives possess confirmed cytotoxic activity towards cancer but also normal...
AbstractThioureas are important sulfur and nitrogen containing compounds and they are useful substan...
A novel series of sulfonamide derivatives (14 compounds) bearing thiourea moieties were efficiently ...
UnrestrictedCancer has emerged as one of the deadliest diseases in the recent past. According to the...
Urea and thiourea represent privileged structures in medicinal chemistry. Indeed, these moieties con...
Urea and thiourea represent privileged structures in medicinal chemistry. Indeed, these moieties con...
Introduction: Urea- and thiourea-based compound has shown a potency to be further developed as antic...
Abstract Background Various thiourea derivatives have been used as starting materials for compounds ...
Mutation of the proto-oncogene K-Ras is one of the most common molecular mechanisms in non-small cel...
A series of dehydroabietic acid (DHAA) acyl-thiourea derivatives were designed and synthesized as po...
Thiourea derivatives demonstrate potent cytotoxic activity against various leukemias and many tumor ...
Two series of bis-substituted thiourea derivatives 40a-e and tri-substituted thiourea derivatives 42...
The specific objective of this research is to investigate the biological activity of thiourea deriva...
Two series of bis-substituted thiourea derivatives 40a-e and tri-substituted thiourea derivatives 42...
A series of 33 novel (thio)urea-containing compounds were initially designed and synthesized as pote...