Multisystem inflammatory syndrome in children associated with new coronavirus infection (Covid-19): Clinical and morphological comparisons
- Ovsyannikov D.Yu.
- Novikova Y.Yu.
- Abramov D.S.
- Angel A.E.
- Glazyrina A.A.
- Kantemirova M.G.
- Kislyakov A.N.
- Kryshova E.S.
- Kurbanova S.Kh.
- Petryaykina E.E.
- Rtishchev A.Yu.
- Tigai Z.G.
- Kharkin A.V.
- Shalatonin M.P.
DOIAbstract
Multisystem Inflammatory Syndrome in Children (MIS-C) associated with new coronavirus infection (COVID-19), with signs of Kawasaki disease (KD) and toxic shock syndrome, well-defined diagnostic criteria, is the most severe manifestation of COVID-19 in pediatric patients. MIS-C is analogous to the cytokine storm in children with COVID-19. The article presents a clinical observation of a child with MIS-C with a lethal outcome. Clinical and anamnestic data, the results of laboratory and instrumental research allowed to diagnose MIS-C in a 2-year-old girl with full KD form. Autopsy results, detailed microscopic examination, which revealed systemic vasculitis of small and medium-sized vessels, inflammatory infiltrates in different organs, are pr...
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