New Synthesis of Functionalized Nicotinamides
- Dyachenko I.V.
- Kalashnik I.N.
- Dyachenko V.D.
- Dorovatovskii P.V.
- Khrustalev V.N.
- Nenajdenko V.G.
DOI Publisher
Pleiades Publishing LtdAbstract
An efficient method has been developed for the synthesis of 6-(alkylsulfanyl)-4-aryl(hetaryl)-N-aryl-5-cyano-2-methylpyridine-3-carboxamides by condensation of aromatic or heteroaromatic aldehydes with cyanothioacetamide and acetoacetanilides in the presence of triethylamine or morpholine, followed by S-alkylation. © 2019, Pleiades Publishing, Ltd
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