Synthesis of Nitriles from Aldehydes with Elongation of the Molecule with Two Carbon Atoms
- Afanasyev O.I.
- Zarochintsev A.
- Petrushina T.
- Cherkasova A.
- Denisov G.
- Cherkashchenko I.
- Chusova O.
- Jinho O.
- Man-Seog C.
- Usanov D.L.
- Semenov S.E.
- Chusov D.
DOI Publisher
WileyAbstract
A new protocol for the synthesis of nitriles from carbonyl compounds with elongation of the molecule with two carbon atoms was developed. It involves a reaction of ethyl cyanoacetate with different aldehydes in the presence of iron pentacarbonyl as a reducing agent. This protocol is very simple and requires only commonly available reagents, with no catalyst or complicated ligands being employed. © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinhei
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