Motivation: Application of phylogenetic footprinting techniques to the analysis of the bacterial regulatory signals results in generation of sets of conserved candidate sites found upstream of orthologous genes. The next step of such analysis should be clustering of sites corresponding to the same signal and thus likely being the binding sites for the same regulator. Results: Here we present an algorithm for clustering of candidate regulatory sites leading to identification of groups of co-regulated genes. Availability: Algorithm was realized using C++ language as console application for Win32. Source code is available upon request
Combining phylogenetic motif discovery and motif clustering to predict co-regulated gene
The genomes of several organisms have been sequenced and the need for methods to analyse the data is...
As noted in the introduction, any mammalian gene may have 50/100, or more, binding sites for transcr...
Motivation: Application of phylogenetic footprinting techniques to the analysis of the bacterial reg...
Phylogenetic footprinting is a method for the discovery of regulatory elements in a set of orthologo...
Abstract Background The learning of global genetic regulatory networks from expression data is a sev...
Identification of transcription factor binding sites is a key task to understand gene regulation mec...
Motivation: Discovery of regulatory motifs in unaligned DNA sequences remains a fundamental problem ...
Large-scale gene expression studies and genomic sequencing projects are providing vast amounts of in...
Introduction The first step toward the modelling of a transcriptional genetic network is to underst...
A new method was developed for revealing of composite clusters of cis-elements in promoters of eukar...
Motivation: Identification of functionally conserved regulatory ele-ments in sequence data from clos...
International audienceBACKGROUND: Identifying gene functional modules is an important step towards e...
Abstract. A model of evolution of a regulatory signal along the phylo-genetic tree of species taking...
Understanding the regulation of gene expression, transcription regulation in particular, is one of t...
Combining phylogenetic motif discovery and motif clustering to predict co-regulated gene
The genomes of several organisms have been sequenced and the need for methods to analyse the data is...
As noted in the introduction, any mammalian gene may have 50/100, or more, binding sites for transcr...
Motivation: Application of phylogenetic footprinting techniques to the analysis of the bacterial reg...
Phylogenetic footprinting is a method for the discovery of regulatory elements in a set of orthologo...
Abstract Background The learning of global genetic regulatory networks from expression data is a sev...
Identification of transcription factor binding sites is a key task to understand gene regulation mec...
Motivation: Discovery of regulatory motifs in unaligned DNA sequences remains a fundamental problem ...
Large-scale gene expression studies and genomic sequencing projects are providing vast amounts of in...
Introduction The first step toward the modelling of a transcriptional genetic network is to underst...
A new method was developed for revealing of composite clusters of cis-elements in promoters of eukar...
Motivation: Identification of functionally conserved regulatory ele-ments in sequence data from clos...
International audienceBACKGROUND: Identifying gene functional modules is an important step towards e...
Abstract. A model of evolution of a regulatory signal along the phylo-genetic tree of species taking...
Understanding the regulation of gene expression, transcription regulation in particular, is one of t...
Combining phylogenetic motif discovery and motif clustering to predict co-regulated gene
The genomes of several organisms have been sequenced and the need for methods to analyse the data is...
As noted in the introduction, any mammalian gene may have 50/100, or more, binding sites for transcr...