Reaction of trifluoroacetylchromenes with 6-aminouracils. Synthesis of pyrido[2,3-d]pyrimidines
- Popova Y.V.
- Osipov D.V.
- Osyanin V.A.
- Klimochkin Y.N.
DOI Publisher
Pleiades Publishing LtdAbstract
The condensation of trifluoroacetyl-substituted 4H-chromenes and 1H-benzo[f]chromenes with 6-amino-1,3-dimethyluracil and 6-aminothiouracil afforded a number of pyrido[2,3-d]pyrimidine derivatives containing a 2-hydroxybenzyl or 2-hydroxynaphthalen-1-ylmethyl group in the 6-position as a result of cascade transformation initiated by Michael addition. © 2017, Pleiades Publishing, Ltd
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