Expression of genes for thioredoxin 1 and thioredoxin 2 in multidrug resistance ovarian carcinoma cells SKVLB
- Kalinina E.V.
- Chernov N.N.
- Saprin A.N.
- Kotova Ya.N.
- Gavrilova Yu.A.
- Chermnykh N.S.
- Shcherbak N.P.
DOI Publisher
Springer Science and Business Media LLCAbstract
The expression of genes for thioredoxin isoforms Trx1 and Trx2 was studied in sensitive SKOV-3 and resistant SKVLB human ovarian carcinoma cells. The development of doxorubicin resistance was accompanied by a significant increase in the expression of TRX1 gene and less pronounced increase in TRX2 gene expression. © Springer Science+Business Media, Inc. 2007
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