Bacteriophages, the viruses of bacteria, have been studied for over a century. They were not only instrumental in laying the foundations of molecular biology, but they are also likely to play crucial roles in shaping our biosphere and may offer a solution to the control of drug-resistant bacterial infections. However, it remains challenging to predict the conditions for bacterial eradication by phage predation, sometimes even under well-defined laboratory conditions, and, most curiously, if the majority of surviving cells are genetically phage-susceptible. Here, I propose that even clonal phage and bacterial populations are generally in a state of continuous 'phenotypic flux', which is caused by transient and nongenetic variation in phage a...
International audienceFor decades, biomedically centered studies of bacteria have focused on mechani...
Phenotypic variation is one of the most conspicuous features of living organisms. Often this variati...
Infections by filamentous phages influence bacterial fitness in various ways. While phage-encoded ac...
The canonical view of phage- bacterial interactions in dense, liquid cultures is that the phage will...
The canonical view of phage - bacterial interactions in dense, liquid cultures is that the phage wil...
Antibiotic resistance evolution in bacteria indicates that one of the challenges faced by phage ther...
Antibiotic resistance evolution in bacteria indicates that one of the challenges faced by phage ther...
The study of bacteriophages, the viruses infecting bacteria, has greatly transformed fundamental and...
As with antibiotics, we can differentiate various acquired mechanisms of bacteria-mediated inhibitio...
Bacteriophages (phages or bacterial viruses) are the most abundant biological entities in our planet...
Bacteriophage (phage) are both predators and evolutionary drivers for bacteria, notably contributing...
© Mattioli 1885.Phages are the obligate parasite of bacteria and have complex interactions with thei...
Complex interactions between bacteriophages and their bacterial hosts play significant roles in shap...
In man-made and natural environments, there is a continuous ongoing interaction between phages and t...
The viruses that infect bacteria, bacteriophages (or phages) are the most abundant biological entiti...
International audienceFor decades, biomedically centered studies of bacteria have focused on mechani...
Phenotypic variation is one of the most conspicuous features of living organisms. Often this variati...
Infections by filamentous phages influence bacterial fitness in various ways. While phage-encoded ac...
The canonical view of phage- bacterial interactions in dense, liquid cultures is that the phage will...
The canonical view of phage - bacterial interactions in dense, liquid cultures is that the phage wil...
Antibiotic resistance evolution in bacteria indicates that one of the challenges faced by phage ther...
Antibiotic resistance evolution in bacteria indicates that one of the challenges faced by phage ther...
The study of bacteriophages, the viruses infecting bacteria, has greatly transformed fundamental and...
As with antibiotics, we can differentiate various acquired mechanisms of bacteria-mediated inhibitio...
Bacteriophages (phages or bacterial viruses) are the most abundant biological entities in our planet...
Bacteriophage (phage) are both predators and evolutionary drivers for bacteria, notably contributing...
© Mattioli 1885.Phages are the obligate parasite of bacteria and have complex interactions with thei...
Complex interactions between bacteriophages and their bacterial hosts play significant roles in shap...
In man-made and natural environments, there is a continuous ongoing interaction between phages and t...
The viruses that infect bacteria, bacteriophages (or phages) are the most abundant biological entiti...
International audienceFor decades, biomedically centered studies of bacteria have focused on mechani...
Phenotypic variation is one of the most conspicuous features of living organisms. Often this variati...
Infections by filamentous phages influence bacterial fitness in various ways. While phage-encoded ac...