Add to ORKGA reproduktív immunológia az orvostudomány azon területe, mely az immunrendszer és a reprodukciós rendszer közötti kapcsolattal (mint például a magzattal szembeni anyai immuntolerancia) foglalkozik. A terhesség tulajdonképpen egy „immunológiai paradoxon”, mivel az anya immunrendszere a fele részben idegen eredetű apai antigéneket is hordozó magzat ellen nem lép fel (a magzat immunológiailag szemi-allogénnek tekinthető), hanem egy igen összetett toleranciamechanizmus révén elfogadja, elősegítve így az egészséges magzat zavartalan fejlődését, majd világra jövetelét. Abban az esetben, ha a tolerancia nem megfelelően alakul ki, számos komplikációhoz vezethet, sőt vetélés is létrejöhet
The abortifacient Mifepristone (RU486) has proven to be a safe, effective, acceptable option for mil...
Dendritic cells (DCs) are professional antigen presenting cells (APC) capable of induction of primar...
Group 3 innate lymphoid cells (ILC3) have been detected in both murine and human decidual tissues wh...
Immune checkpoint molecules, like CTLA-4, TIM-3, PD-1, are negative regulators of immune responses t...
Background: Immune checkpoints are molecules that regulate the function of immune cells and control ...
The semi-allogeneic fetus develops in a uniquely immune tolerant environment within the uterus. For ...
Understanding how the antigenically foreign fetus escapes attack by maternal lymphoid cells has long...
Abstract Background Our goal with this study was to investigate the contribution of PD-1/PD-L1 immun...
Tolerance of the fetus by the maternal immune system is regulated through various mechanisms involvi...
In normal pregnancy, the maternal immune system is directed towards tolerance or suppression in orde...
Preeclampsia is a pregnancy-specific disease which is characterized by abnormal placentation, endoth...
Abstract Problem: The T-cell immunoglobulin and mucin domain (TIM) family is a relatively newly des...
The semi-allogeneic fetus derives half of its genetic maternal from the mother. The other half, inhe...
Mammalian pregnancy is an immunological paradox. The foetus, which expresses both paternal and mater...
<div><p>The abortifacient Mifepristone (RU486) has proven to be a safe, effective, acceptable option...
The abortifacient Mifepristone (RU486) has proven to be a safe, effective, acceptable option for mil...
Dendritic cells (DCs) are professional antigen presenting cells (APC) capable of induction of primar...
Group 3 innate lymphoid cells (ILC3) have been detected in both murine and human decidual tissues wh...
Immune checkpoint molecules, like CTLA-4, TIM-3, PD-1, are negative regulators of immune responses t...
Background: Immune checkpoints are molecules that regulate the function of immune cells and control ...
The semi-allogeneic fetus develops in a uniquely immune tolerant environment within the uterus. For ...
Understanding how the antigenically foreign fetus escapes attack by maternal lymphoid cells has long...
Abstract Background Our goal with this study was to investigate the contribution of PD-1/PD-L1 immun...
Tolerance of the fetus by the maternal immune system is regulated through various mechanisms involvi...
In normal pregnancy, the maternal immune system is directed towards tolerance or suppression in orde...
Preeclampsia is a pregnancy-specific disease which is characterized by abnormal placentation, endoth...
Abstract Problem: The T-cell immunoglobulin and mucin domain (TIM) family is a relatively newly des...
The semi-allogeneic fetus derives half of its genetic maternal from the mother. The other half, inhe...
Mammalian pregnancy is an immunological paradox. The foetus, which expresses both paternal and mater...
<div><p>The abortifacient Mifepristone (RU486) has proven to be a safe, effective, acceptable option...
The abortifacient Mifepristone (RU486) has proven to be a safe, effective, acceptable option for mil...
Dendritic cells (DCs) are professional antigen presenting cells (APC) capable of induction of primar...
Group 3 innate lymphoid cells (ILC3) have been detected in both murine and human decidual tissues wh...