International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-infected patients present lymphopenia, which we recently reported as being related to abnormal programmed cell death. As an efficient humoral response requires CD4 T-cell help, we hypothesized that the propensity of CD4 T cells to die may impact the quantity and quality of the humoral response in acutely infected individuals. In addition to specific immunoglobulins (Ig)A, IgM, and IgG against SARS-CoV-2 nucleocapsid (N), membrane (M), and spike (S1) proteins, we assessed the quality of IgG response by measuring the avidity index. Because the S protein represents the main target for neutralization and antibody-...
The preexistence of humoral immunity, which cross-reacts with severe acute respiratory syndrome coro...
There is an urgent need for effective treatment and preventive vaccine to contain this devastating g...
Background The immune response to SARS-CoV-2 virus, the cause of COVID-19, is complex. Antibody medi...
International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syn...
International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syn...
International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syn...
International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syn...
International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syn...
International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syn...
International audienceSevere SARS-CoV-2 infections are characterized by lymphopenia, but the mechani...
International audienceSevere SARS-CoV-2 infections are characterized by lymphopenia, but the mechani...
International audienceSevere SARS-CoV-2 infections are characterized by lymphopenia, but the mechani...
International audienceSevere SARS-CoV-2 infections are characterized by lymphopenia, but the mechani...
More than a year after the start of the pandemic, COVID-19 remains a global health emergency. Althou...
Cellular and humoral immunity to SARS-CoV-2 is critical to control primary infection and correlates ...
The preexistence of humoral immunity, which cross-reacts with severe acute respiratory syndrome coro...
There is an urgent need for effective treatment and preventive vaccine to contain this devastating g...
Background The immune response to SARS-CoV-2 virus, the cause of COVID-19, is complex. Antibody medi...
International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syn...
International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syn...
International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syn...
International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syn...
International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syn...
International audienceAbstract In addition to an inflammatory reaction, Severe Acute Respiratory Syn...
International audienceSevere SARS-CoV-2 infections are characterized by lymphopenia, but the mechani...
International audienceSevere SARS-CoV-2 infections are characterized by lymphopenia, but the mechani...
International audienceSevere SARS-CoV-2 infections are characterized by lymphopenia, but the mechani...
International audienceSevere SARS-CoV-2 infections are characterized by lymphopenia, but the mechani...
More than a year after the start of the pandemic, COVID-19 remains a global health emergency. Althou...
Cellular and humoral immunity to SARS-CoV-2 is critical to control primary infection and correlates ...
The preexistence of humoral immunity, which cross-reacts with severe acute respiratory syndrome coro...
There is an urgent need for effective treatment and preventive vaccine to contain this devastating g...
Background The immune response to SARS-CoV-2 virus, the cause of COVID-19, is complex. Antibody medi...