Self-assembled peptides possess remarkable potential as targeted drug delivery systems and key applications dwell anti-cancer therapy. Peptides can self-assemble into nanostructures of diverse sizes and shapes in response to changing environmental conditions (pH, temperature, ionic strength). Herein, we investigated the development of self-assembled peptide-based nanofibers (NFs) with the inclusion of a cell-penetrating peptide (namely gH625) and a matrix metalloproteinase-9 (MMP-9) responsive sequence, which proved to enhance respectively the penetration and tumor-triggered cleavage to release Doxorubicin in Triple Negative Breast Cancer cells where MMP-9 levels are elevated. The NFs formulation has been optimized via critical micelle conc...
Synthesis of nanomaterials via 'molecular self-assembly' allows one to define the properties of the ...
Data management plan for the grant, "New approach based on enzyme stimulating of peptides for target...
In this study, we report a facile method to construct a bioactive (poly(phenylalanine)-b-poly(t-hist...
Self-assembled peptides possess remarkable potential as targeted drug delivery systems and key appli...
Despite scientific progress, cancer still remains a challenge and therapies on the market present se...
We prepared nanoscale, modularizable, self-assembled peptide nanoarchitectures with diameters less o...
Peptide self-assembly has a profound biological significance since self-assembled bioactive peptides...
A central challenge in cancer care is to ensure that therapeutic compounds reach their targets. One ...
Peptide amphiphiles (PAs) self-assemble into supramolecular nanofiber gels that provide a suitable e...
How do you design a peptide building block to make 2-dimentional nanowebs and 3-dimensional fibrous ...
Expression levels of enzymes dictate the difference between health and disease in many cases, includ...
(Arginine-alanine-aspartic acid-alanine)4 ((RADA)4) nanoscaffolds are excellent candidates for use a...
International audienceNFL-TBS.40-63 peptide is a recently discovered peptide derived from the light ...
Photodynamic therapy (PDT) is a highly promising therapeutic modality for cancer treatment. The deve...
Cancer creates one of the most significant public health problems not just in the United States, but...
Synthesis of nanomaterials via 'molecular self-assembly' allows one to define the properties of the ...
Data management plan for the grant, "New approach based on enzyme stimulating of peptides for target...
In this study, we report a facile method to construct a bioactive (poly(phenylalanine)-b-poly(t-hist...
Self-assembled peptides possess remarkable potential as targeted drug delivery systems and key appli...
Despite scientific progress, cancer still remains a challenge and therapies on the market present se...
We prepared nanoscale, modularizable, self-assembled peptide nanoarchitectures with diameters less o...
Peptide self-assembly has a profound biological significance since self-assembled bioactive peptides...
A central challenge in cancer care is to ensure that therapeutic compounds reach their targets. One ...
Peptide amphiphiles (PAs) self-assemble into supramolecular nanofiber gels that provide a suitable e...
How do you design a peptide building block to make 2-dimentional nanowebs and 3-dimensional fibrous ...
Expression levels of enzymes dictate the difference between health and disease in many cases, includ...
(Arginine-alanine-aspartic acid-alanine)4 ((RADA)4) nanoscaffolds are excellent candidates for use a...
International audienceNFL-TBS.40-63 peptide is a recently discovered peptide derived from the light ...
Photodynamic therapy (PDT) is a highly promising therapeutic modality for cancer treatment. The deve...
Cancer creates one of the most significant public health problems not just in the United States, but...
Synthesis of nanomaterials via 'molecular self-assembly' allows one to define the properties of the ...
Data management plan for the grant, "New approach based on enzyme stimulating of peptides for target...
In this study, we report a facile method to construct a bioactive (poly(phenylalanine)-b-poly(t-hist...