Characterization of Contractile Forces Generated by Stretch Marks Fibroblasts: In Vitro Study
- Pensato R.
- Hersant B.
- Pizza C.
- Errico C.
- D'Andrea F.
- Rega U.
- Persichetti P.
- Meningaud J. P.
- La Padula S.
DOIAbstract
Abstract: Authors present a study about the contraction forces observed in striae distensae fibroblasts (SMF) in a collagen scaffold. Collagen lattices were used to study the mechanical behavior of SDF within the collagen matrix compared to the lattices produced using the healthy skin derived fibroblasts (NSF). A Forcebox device was used to measure the contractile forces. Striae Rubrae fibroblast’s contractile force was by 28% greater than that generated by the NSF and striae albae fibroblasts (P<0.05). Anomalies and especially differences in forces generated by SMF were observed through all our experiments. These findings complete and corroborate the results and information published in our previous studies. Level of Evidence V: This journ...
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