Add to ORKGIdebenone is a synthetic analogue of coenzyme Q10 with antioxidant properties. The present study investigated the antioxidant activity of idebenone in the rescue of acoustic trauma. Noise-induced hearing loss was induced by exposing guinea pigs to a continuous pure tone and idebenone was injected intraperitoneally 1 h before noise exposure and once daily for 3 days. Guinea pigs treated with idebenone showed significantly smaller auditory threshold shifts than unprotected control animals. Missing and apoptotic cells were identified with scanning electron microscopy and terminal deoxynucleotidyl transferase-mediated dUTP nick end labelling assay. Protected animals presented a lesser extent of both apoptotic activation and hair cell loss in th...
Ferulic acid (FA) is a phenolic compound whose neuroprotective activity was extensively studied in v...
BACKGROUND: Data from animal studies show that antioxidants can compensate against noise-induced st...
Data from animal studies show that antioxidants can compensate against noise-induced stress and sens...
Idebenone, a synthetic analogue of coenzyme Q, attenuates noise-induced hearing loss by virtue of it...
Idebenone, a synthetic analogue of coenzyme Q, attenuates noise-induced hearing loss by virtue of it...
Oxidative stress plays a significant role in noise-induced hearing loss (NIHL), as it largely partic...
Background: Antioxidants and the duration of treatment after noise exposure on hearing recovery are ...
Increasing evidence suggests the involvement of oxidative stress in noise-induced hearing loss. The ...
The mitochondrial respiratory chain is a powerful source of reactive oxygen species (ROS) also in no...
Preventing noise-induced hearing loss (NIHL) by antioxidants is based on the hypothesis that generat...
The mitochondrial respiratory chain is a powerful source of reactive oxygen species (ROS) also in no...
Oxidative stress is considered a major cause of the structural and functional changes associated wit...
Ferulic acid (FA) is a phenolic compound whose neuroprotective activity was extensively studied in v...
To investigate the protective effect of two anti-reactive oxygen species (ROS) substances, copper-zi...
Abstract Conclusion: Our results are in agreement with the general idea that natural antioxidants ac...
Ferulic acid (FA) is a phenolic compound whose neuroprotective activity was extensively studied in v...
BACKGROUND: Data from animal studies show that antioxidants can compensate against noise-induced st...
Data from animal studies show that antioxidants can compensate against noise-induced stress and sens...
Idebenone, a synthetic analogue of coenzyme Q, attenuates noise-induced hearing loss by virtue of it...
Idebenone, a synthetic analogue of coenzyme Q, attenuates noise-induced hearing loss by virtue of it...
Oxidative stress plays a significant role in noise-induced hearing loss (NIHL), as it largely partic...
Background: Antioxidants and the duration of treatment after noise exposure on hearing recovery are ...
Increasing evidence suggests the involvement of oxidative stress in noise-induced hearing loss. The ...
The mitochondrial respiratory chain is a powerful source of reactive oxygen species (ROS) also in no...
Preventing noise-induced hearing loss (NIHL) by antioxidants is based on the hypothesis that generat...
The mitochondrial respiratory chain is a powerful source of reactive oxygen species (ROS) also in no...
Oxidative stress is considered a major cause of the structural and functional changes associated wit...
Ferulic acid (FA) is a phenolic compound whose neuroprotective activity was extensively studied in v...
To investigate the protective effect of two anti-reactive oxygen species (ROS) substances, copper-zi...
Abstract Conclusion: Our results are in agreement with the general idea that natural antioxidants ac...
Ferulic acid (FA) is a phenolic compound whose neuroprotective activity was extensively studied in v...
BACKGROUND: Data from animal studies show that antioxidants can compensate against noise-induced st...
Data from animal studies show that antioxidants can compensate against noise-induced stress and sens...