Plasma deposition and treatment processes for micro- and nano-patterning biomedical polymers

The processes of plasma deposition and treatment for micro- and nano-patterning biomedical polymers were described. The deposition process consists of cell repulsive coatings through physical masks to produce patterned surfaces. The chemical composition of the plasma modified surfaces was tightly correlated to the relative percentage of intact ethylene oxide units in the coatings. The response of cells in terms of adhesion and spreading shows cells aligned along cell-adhesive tracks avoiding the contact with the totally cell repulsive coated areas